Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673380 | 0.85 | STAT3 (0.44) | STAT3LMNAADRB2PIM1GSK3A | |
| SCHEMBL12835792 | 0.82 | STAT3 (0.42) | STAT3LMNAADRB2PIM1GSK3A | |
| SCHEMBL1516285 | 0.81 | ADORA1 (0.36) | STAT3ADORA1ADRB2PIM1GSK3A | |
| SCHEMBL12836206 | 0.81 | KMT2A (0.39) | STAT3LMNAADRB2PIM1GSK3A | |
| SCHEMBL12835793 | 0.81 | STAT3 (0.38) | STAT3LMNAADRB2PIM1GSK3A | |
| SCHEMBL9782871 | 0.81 | STAT3 (0.39) | STAT3LMNAADRB2PIM1GSK3A | |
| SCHEMBL12836216 | 0.79 | ADORA1 (0.37) | STAT3ADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL9568366 | 0.77 | MAPT (0.40) | LMNAKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9568299 | 0.77 | MAPT (0.40) | LMNAKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL1699779 | 0.75 | LMNA (0.47) | LMNAPIM1GSK3AGSK3BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031745-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2011-03-17 | — | — | WO | disclosed |