Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1514462 | 0.99 | GAA (0.42) | GAAP2RY12CHRM2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL1514433 | 0.99 | GAA (0.42) | GAAP2RY12CHRM2CYP3A4CYP2C9 | |
| SCHEMBL3404525 | 0.82 | ALDH1A1 (0.51) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL12836341 | 0.82 | P2RY12 (0.41) | GAAP2RY12CHRM2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL1514729 | 0.81 | P2RY12 (0.40) | GAAP2RY12CHRM2CYP3A4CYP2C9 | |
| SCHEMBL1514258 | 0.81 | CTSK (0.47) | P2RY12PIM1PIM3RETDPP4 | |
| SCHEMBL12835966 | 0.75 | HRH2 (0.44) | P2RY12RET | |
| SCHEMBL11441054 | 0.73 | KDM4E (0.51) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL18430426 | 0.73 | KDM4E (0.47) | GAAMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL12895644 | 0.73 | KDM4E (0.45) | GAAMAPTKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025799-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-03-03 | — | — | WO | disclosed |