Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514345 | 0.96 | BPTF (0.61) | BPTFALDH1A1MAPTGAAALOX15 | |
| SCHEMBL12835960 | 0.94 | ALDH1A1 (0.62) | BPTFALDH1A1MAPTGAAALOX15 | |
| SCHEMBL13569708 | 0.78 | BPTF (0.58) | BPTFALDH1A1MAPTGAAALOX15 | |
| SCHEMBL1514467 | 0.76 | BPTF (0.92) | BPTFALDH1A1MAPTGAAALOX15 | |
| SCHEMBL18830905 | 0.76 | BPTF (0.61) | BPTFALDH1A1MAPTGAAALOX15 | |
| SCHEMBL18830918 | 0.74 | ALDH1A1 (0.62) | BPTFALDH1A1MAPTGAAALOX15 | |
| SCHEMBL18506968 | 0.74 | PNMT (0.39) | BPTFALDH1A1MAPTGAAALOX15 | |
| SCHEMBL11919882 | 0.73 | BPTF (0.63) | BPTFALDH1A1MAPTGAAALOX15 | |
| SCHEMBL620749 | 0.72 | BPTF (1.00) | BPTFALDH1A1MAPTGAAALOX15 | |
| SCHEMBL1514227 | 0.72 | BPTF (0.61) | BPTFALDH1A1MAPTGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025799-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-03-03 | — | — | WO | disclosed |