Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836701 | 1.00 | TYR (0.47) | TYRLTB4RLTB4R2ALDH1A1KDM4E | |
| SCHEMBL12836700 | 1.00 | TYR (0.47) | TYRLTB4RLTB4R2ALDH1A1KDM4E | |
| SCHEMBL12883167 | 0.85 | ACHE (0.59) | LTB4RLTB4R2ALDH1A1KDM4EHTT | |
| SCHEMBL21199753 | 0.85 | ALDH1A1 (0.50) | LTB4RLTB4R2ALDH1A1KDM4EHTT | |
| SCHEMBL12883163 | 0.85 | ACHE (0.59) | LTB4RLTB4R2ALDH1A1KDM4EHTT | |
| SCHEMBL12883164 | 0.85 | ACHE (0.59) | LTB4RLTB4R2ALDH1A1KDM4EHTT | |
| SCHEMBL13715441 | 0.83 | KMT2A (0.49) | LTB4RLTB4R2ALDH1A1KDM4EHTT | |
| SCHEMBL3665975 | 0.83 | KMT2A (0.49) | LTB4RLTB4R2ALDH1A1KDM4EHTT | |
| SCHEMBL13715515 | 0.83 | KMT2A (0.49) | LTB4RLTB4R2ALDH1A1KDM4EHTT | |
| SCHEMBL22230670 | 0.82 | KMT2A (0.47) | LTB4RLTB4R2ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034849-A1 | NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS | AURIMED PHARMA, INC. (US) | 2011-03-24 | — | — | WO | disclosed |