Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14553043 | 0.87 | SCD (0.42) | SCDTRPV1 | |
| SCHEMBL992405 | 0.84 | SCD (0.70) | SCD | |
| SCHEMBL15190370 | 0.79 | SCD (0.51) | SCDGAAALDH1A1MAPTMAPK1 | |
| SCHEMBL3666246 | 0.72 | SCD (0.77) | SCD | |
| SCHEMBL1819943 | 0.70 | SCD (0.54) | SCDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL3670032 | 0.68 | SCD (0.74) | SCD | |
| SCHEMBL995031 | 0.68 | HSD11B1 (0.59) | SCDGAAALDH1A1MAPTMAPK1 | |
| SCHEMBL3667618 | 0.68 | SCD (0.54) | SCDALDH1A1KMT2A | |
| SCHEMBL1378991 | 0.67 | SCD (1.00) | SCD | |
| SCHEMBL1600528 | 0.67 | SCD (0.71) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012709-A1 | NOVEL INHIBITORS OF STEAROYL-CoA-DESATURASE-1 AND THEIR USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-10 | — | — | US | disclosed |
| WO-2011030312-A1 | NOVEL INHIBITORS OF STEAROYL-CoA-DESATURASE-1 AND THEIR USES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012709-A1 | NOVEL INHIBITORS OF STEAROYL-CoA-DESATURASE-1 AND THEIR USES | SCD, SCD5, FADS2 | SCD 1/4885GAA 1368/4885ALDH1A1 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.