Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.58 |
| ▸ | BCR | P11274 | 14/20 | 0.58 |
| ▸ | PRKCA | P17252 | 12/20 | 0.53 |
| ▸ | SRC | P12931 | 10/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 9/20 | 0.53 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKACG | P22612 | 1/20 | 0.53 |
| ▸ | PRKACB | P22694 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.47 |
| ▸ | PRKCG | P05129 | 2/20 | 0.47 |
| ▸ | PRKCB | P05771 | 2/20 | 0.47 |
| ▸ | PRKCH | P24723 | 2/20 | 0.47 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8246544 | 0.88 | ABL1 (0.58) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL8255847 | 0.86 | PIK3CG (0.59) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL11924749 | 0.84 | ABL1 (0.62) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL8252396 | 0.83 | ABL1 (0.77) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL8253620 | 0.82 | PRKCA (0.55) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL11929046 | 0.80 | ABL1 (0.53) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL8246547 | 0.78 | ABL1 (0.58) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7476769 | 0.74 | ABL1 (1.00) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL6106194 | 0.72 | CDK2 (0.63) | ABL1BCRPRKCAPRKCDKDR | |
| SCHEMBL4084867 | 0.72 | ABL1 (0.77) | ABL1BCRPRKCASRCPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897572-B1 | Theraputic methods for type I diabetes | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2011-03-01 | — | — | US | disclosed |