Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 1.00 |
| ▸ | BCR | P11274 | 13/20 | 1.00 |
| ▸ | PRKCA | P17252 | 11/20 | 0.73 |
| ▸ | SRC | P12931 | 10/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.73 |
| ▸ | EGFR | P00533 | 3/20 | 0.73 |
| ▸ | PRKACA | P17612 | 1/20 | 0.73 |
| ▸ | PRKACG | P22612 | 1/20 | 0.73 |
| ▸ | PRKACB | P22694 | 1/20 | 0.73 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.69 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.69 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.69 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.63 |
| ▸ | PRKCG | P05129 | 2/20 | 0.63 |
| ▸ | PRKCB | P05771 | 2/20 | 0.63 |
| ▸ | PRKCH | P24723 | 2/20 | 0.63 |
| ▸ | PRKCI | P41743 | 2/20 | 0.63 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.63 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469833 | 0.89 | ABL1 (0.81) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL4084867 | 0.87 | ABL1 (0.77) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7467324 | 0.86 | ABL1 (0.76) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL29618427 | 0.84 | ABL1 (0.85) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL6254782 | 0.84 | ABL1 (1.00) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7461678 | 0.84 | ABL1 (0.73) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL1465 | 0.84 | ABL1 (1.00) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7474612 | 0.84 | PIK3CG (0.76) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL17070834 | 0.84 | ABL1 (0.72) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7528647 | 0.84 | ABL1 (0.72) | ABL1BCRPRKCASRCPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098473-A1 | REAGENTS AND METHODS FOR ANALYSIS OF PROTEINS AND METABOLITES TARGETED BY COVALENT PROBES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-31 | — | — | WO | disclosed |
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |