Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399936 | 0.85 | FFAR1 (0.44) | FFAR1HTTALDH1A1MAPTHSP90AA1 | |
| SCHEMBL404504 | 0.85 | FFAR1 (0.44) | FFAR1HTTALDH1A1MAPTHSP90AA1 | |
| SCHEMBL440373 | 0.74 | HTT (0.45) | HTTALDH1A1MAPTHSP90AA1NPSR1 | |
| SCHEMBL400777 | 0.70 | HPGDS (0.44) | — | |
| SCHEMBL1095096 | 0.70 | — | — | |
| SCHEMBL3016953 | 0.69 | GAA (0.51) | RAB9A | |
| SCHEMBL3016958 | 0.69 | GAA (0.51) | RAB9A | |
| SCHEMBL1105523 | 0.69 | S1PR2 (0.46) | FFAR1HTTALDH1A1MAPTHSP90AA1 | |
| SCHEMBL404589 | 0.69 | S1PR2 (0.46) | FFAR1HTTALDH1A1MAPTHSP90AA1 | |
| SCHEMBL404588 | 0.69 | S1PR2 (0.46) | FFAR1HTTALDH1A1MAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295402-A2 | Antibacterial agents | The University of Washington (US) | 2011-03-16 | — | — | EP | disclosed |