Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3016953 | 1.00 | GAA (0.51) | GAARAB9ACYP26A1TAS1R3TAS1R1 | |
| SCHEMBL404522 | 0.95 | GAA (0.53) | GAARAB9ACYP26A1 | |
| SCHEMBL7448811 | 0.85 | GAA (0.54) | GAARAB9ACYP26A1TAS1R3TAS1R1 | |
| SCHEMBL7448810 | 0.85 | GAA (0.54) | GAARAB9ACYP26A1TAS1R3TAS1R1 | |
| SCHEMBL1109199 | 0.84 | CYP26A1 (0.59) | GAARAB9ACYP26A1TAS1R3TAS1R1 | |
| SCHEMBL438972 | 0.84 | — | — | |
| SCHEMBL13245474 | 0.83 | GAA (0.57) | GAARAB9ATAS1R3TAS1R1 | |
| SCHEMBL3007354 | 0.83 | GAA (0.45) | GAARAB9ACYP26A1TAS1R3TAS1R1 | |
| SCHEMBL3007360 | 0.83 | GAA (0.45) | GAARAB9ACYP26A1TAS1R3TAS1R1 | |
| SCHEMBL3007363 | 0.83 | GAA (0.45) | GAARAB9ACYP26A1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20170088549-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2017-03-30 | — | — | US | disclosed |
| EP-2170814-B1 | ANTIBACTERIAL AGENTS | ACHAOGEN INC (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2662353-A2 | Antibacterial agents | Achaogen, Inc. (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088549-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | GAA 70/4885RAB9A 509/4885CYP26A1 159/4885 |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | GAA 70/4885RAB9A 509/4885CYP26A1 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.