⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687901 | 0.72 | CA2 (0.32) | — | |
| SCHEMBL6200636 | 0.69 | — | — | |
| SCHEMBL1109972 | 0.69 | — | — | |
| SCHEMBL14895482 | 0.69 | — | — | |
| SCHEMBL9217325 | 0.67 | — | — | |
| SCHEMBL1757094 | 0.67 | — | — | |
| SCHEMBL1484508 | 0.67 | — | — | |
| SCHEMBL20657063 | 0.67 | — | — | |
| SCHEMBL940410 | 0.67 | — | — | |
| SCHEMBL30315 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958928-B1 | ESTRA-1,3,5(10),16-TETRAENE-3-CARBOXAMIDES FOR INHIBITION OF 17.BETA.-HYDROXYSTEROID DEHYDROGENASE (AKR1 C3) | Bayer Pharma AG (DE) | 2018-03-28 | — | — | EP | claimed |
| EP-2089384-B1 | 2-(PIPERIDIN-4-YL)-4-PHENOXY-OR PHENYLAMINO-PYRIMIDINE DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2015-08-05 | — | — | EP | claimed |
| US-20120088912-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS, INC. (US) | 2012-04-12 | — | — | US | claimed |
| EP-1569911-B1 | INDAZOLE DERIVATIVES AS CRF ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-02 | — | — | EP | claimed |
| EP-0106093-B1 | IODOPROPARGYLSULFAMIDE | BAYER AG (DE) | 1986-11-20 | — | — | EP | claimed |
| EP-0106093-A2 | Iodopropargylsulfamide | BAYER AG (DE) | 1984-04-25 | — | — | EP | claimed |
| EP-0026611-B1 | ANTIBACTERIAL SULPHONAMIDES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-02-01 | — | — | EP | claimed |
| EP-4371979-A1 | FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| CN-117693500-A | Carboxamide derivative and agricultural/horticultural plant disease control agent | 组合化学工业株式会社 | 2024-03-12 | — | — | CN | disclosed |
| CN-219835910-U | Hemostatic sponge and hemostatic sponge system | 上海赢生医疗科技有限公司 | 2023-10-17 | — | — | CN | disclosed |
| US-11641857-B2 | Unusually potent ABA receptor pan-antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-09 | — | — | US | disclosed |
| WO-2023286855-A1 | FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT | クミアイ化学工業株式会社 | 2023-01-19 | — | — | WO | disclosed |
| US-20220403051-A1 | A DOTA binding chimeric antigen receptor for cellular therapy | UNIV PENNSYLVANIA (US) | 2022-12-22 | — | — | US | disclosed |
| WO-1998016514-A1 | ORTHO-SULFONAMIDO BICYCLIC HETEROARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |
| WO-1998016503-A2 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |
| CN-1055537-A | 3, two replacement-2-different azoles alkane of 5-and different azoles, its preparation method contain the preparation and the application thereof of this composition | HOECHST AG (DE) | 1991-10-23 | — | — | CN | disclosed |
| EP-0106093-B1 | IODOPROPARGYLSULFAMIDE | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |
| US-4457930-A | FUNGICIDES, BACTERICIDES, SLIMICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |
| EP-0106093-A2 | Iodopropargylsulfamide | BAYER AG (DE) | 1984-04-25 | — | — | EP | disclosed |
| EP-0106093-A2 | Iodopropargylsulfamide | BAYER AG (DE) | 1984-04-25 | — | — | EP | disclosed |