⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725195 | 0.73 | — | — | |
| SCHEMBL4805970 | 0.73 | — | — | |
| SCHEMBL14351421 | 0.71 | — | — | |
| SCHEMBL2127275 | 0.71 | — | — | |
| Sulfamate SCHEMBL21409596 | 0.71 | CA2 (0.48) | — | |
| SCHEMBL3474802 | 0.71 | — | — | |
| SCHEMBL5708005 | 0.71 | — | — | |
| SCHEMBL1644673 | 0.69 | CA2 (0.46) | — | |
| SCHEMBL1283757 | 0.69 | — | — | |
| SCHEMBL12854157 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116881-A1 | KIF MODULATOR COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-12612395-B2 | Rocaglate derivatives and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2026-04-28 | — | — | US | disclosed |
| WO-2025076059-A1 | ROCAGLATE DERIVATIVES AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-04-10 | — | — | WO | disclosed |
| US-20250115593-A1 | ROCAGLATE DERIVATIVES AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-04-10 | — | — | US | disclosed |
| US-20250059220-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-02-20 | — | — | US | disclosed |
| CN-117321052-A | Alkyne compound as HPK1 inhibitor and application thereof | 南京再明医药有限公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2023135330-A1 | DEOXYCYTIDINE KINASE INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-07-20 | — | — | WO | disclosed |
| WO-2023121939-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2023-06-29 | — | — | WO | disclosed |
| EP-3697769-B1 | 6-SUBSTITUTED 3-FLUORO-2-PYRIDINALDOXIME, 3-FLUORO-2-PYRIDINE HYDROXAMIC ACID, AND 3-FLUORO-2-PYRIDINAMIDOXIME SCAFFOLDS | CENTRE NAT RECH SCIENT (FR) | 2023-02-15 | — | — | EP | disclosed |
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| WO-2019076986-A1 | 6-SUBSTITUTED 3-FLUORO-2-PYRIDINALDOXIME, 3-FLUORO-2-PYRIDINE HYDROXAMIC ACID, AND 3-FLUORO-2-PYRIDINAMIDOXIME SCAFFOLDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-04-25 | — | — | WO | disclosed |
| EP-3473618-A1 | 6-SUBSTITUTED 3-FLUORO-2-PYRIDINALDOXIME, 3-FLUORO-2-PYRIDINE HYDROXAMIC ACID, AND 3-FLUORO-2-PYRIDINAMIDOXIME SCAFFOLDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-04-24 | — | — | EP | disclosed |
| US-9290529-B2 | Carbonic anhydrase inhibitors and method of their production | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY, V.V.I. (CZ) | 2016-03-22 | — | — | US | disclosed |
| US-9238628-B2 | Phenyl amino pyrimidine compounds and uses thereof | YM Biosicences Australia PTY LTD (US) | 2016-01-19 | — | — | US | disclosed |
| EP-2822934-A1 | PHENICOL ANTIBACTERIALS | Zoetis LLC (US) | 2015-01-14 | — | — | EP | disclosed |
| US-20140303390-A1 | CARBONIC ANHYDRASE INHIBITORS AND METHOD OF THEIR PRODUCTION | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2014-10-09 | — | — | US | disclosed |
| EP-2771015-A1 | CARBONIC ANHYDRASE INHIBITORS AND METHOD OF THEIR PRODUCTION | Ústav Organické Chemie A Biochemie Akademie Ved Ceské Republiky, v.v.i. (CZ) | 2014-09-03 | — | — | EP | disclosed |
| US-20140011803-A1 | PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE LLC | 2014-01-09 | — | — | US | disclosed |
| WO-2013134061-A1 | PHENICOL ANTIBACTERIALS | ZOETIS LLC (US) | 2013-09-12 | — | — | WO | disclosed |
| WO-2013060307-A1 | CARBONIC ANHYDRASE INHIBITORS AND METHOD OF THEIR PRODUCTION | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY, V.V.I. (CZ) | 2013-05-02 | — | — | WO | disclosed |