SCHEMBL1283873

SCHEMBL1283873

O=C(Cl)CCCC1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
HPGD P15428 1/20 0.46
P2RX7 Q99572 1/20 0.44
SIGMAR1 Q99720 3/20 0.44
KDM5A P29375 3/20 0.44
PHF8 Q9UPP1 3/20 0.44
KDM2A Q9Y2K7 3/20 0.44
KDM4C Q9H3R0 2/20 0.44
KDM4A O75164 1/20 0.44
EPHX1 P07099 1/20 0.42
NAAA Q02083 2/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8788705 0.98 CYP1A2 (0.43) CYP1A2HPGDP2RX7SIGMAR1KDM5A
SCHEMBL25192919 0.96 CYP1A2 (0.43) CYP1A2HPGDP2RX7SIGMAR1KDM5A
SCHEMBL384147 0.94 KDM5A (0.50) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL9061840 0.92 KDM5A (0.53) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL9089300 0.92 KDM5A (0.53) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL19612642 0.92 KDM5A (0.53) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL6519311 0.89 KDM5A (0.51) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL6521504 0.89 KDM5A (0.51) CYP1A2HPGDSIGMAR1KDM5APHF8
SCHEMBL1595294 0.86 HPGD (0.53) CYP1A2HPGDP2RX7EPHX1NPC1
SCHEMBL209174 0.86 HPGD (0.53) CYP1A2HPGDP2RX7EPHX1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709710-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2026-03-18 EP disclosed
WO-2025044765-A1 OXIME ESTER COMPOUND, PHOTORESIST, AND USE THEREOF 北京云基科技股份有限公司 2025-03-06 WO disclosed
US-20240391870-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2024-11-28 US disclosed
WO-2024233750-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2024-11-14 WO disclosed
EP-4430026-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2024-09-18 EP disclosed
CN-118451059-A Ionizable cationic lipids for RNA delivery 阿克丘勒斯治疗公司 2024-08-06 CN disclosed
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2023-09-21 US disclosed
WO-2023086514-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2023-05-19 WO disclosed
WO-2023086514-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2023-05-19 WO disclosed
EP-0569386-B1 BRIDGED CYCLIC KETAL DERIVATIVES GLAXO GROUP LTD (GB) 1996-09-25 EP disclosed
US-5510375-A VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS WARNER-LAMBERT COMPANY (US) 1996-04-23 US disclosed
EP-0663401-A1 MORPHINAN DERIVATIVE AND MEDICINAL USE TORAY INDUSTRIES, INC. (JP) 1995-07-19 EP disclosed
EP-0569386-A1 BRIDGED CYCLIC KETAL DERIVATIVES. GLAXO GROUP LTD (GB) 1993-11-18 EP disclosed
EP-0497091-A1 Bridged cyclic ketal derivatives GLAXO GROUP LIMITED (GB) 1992-08-05 EP disclosed
WO-1992012159-A1 BRIDGED CYCLIC KETAL DERIVATIVES GLAXO GROUP LIMITED (GB) 1992-07-23 WO disclosed
EP-0447188-A2 7-Oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic diseases E.R. SQUIBB & SONS, INC. (US) 1991-09-18 EP disclosed
EP-0403090-A1 7-oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease E.R. SQUIBB & SONS, INC. (US) 1990-12-19 EP disclosed
US-4977174-A Anticoagulants, antischemic agents E. R. SQUIBB & SONS, INC. (US) 1990-12-11 US disclosed
US-4108857-A CNS DEPRESSANTS, ANALGESICS, PSYCHOMOTOR ACTION STERLING DRUG INC. (US) 1978-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391870-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY NSUN3, POLRMT, NPC1L1 CYP1A2 4491/4885HPGD 4518/4885P2RX7 3817/4885
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY NSUN3, POLRMT, NPC1L1 CYP1A2 4491/4885HPGD 4518/4885P2RX7 3817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.