SCHEMBL128396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28009643	0.82	TSHR (0.41)	CYP3A4CYP2D6CYP2C19TSHRHIF1A
	SCHEMBL2370519	0.81	MAPK1 (0.54)	ALOX15CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL873711	0.81	HPGD (0.56)	ALOX15TSHRALDH1A1MEN1KMT2A
	SCHEMBL14125147	0.81	PTGDR2 (0.42)	ALOX15CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL15011014	0.79	TRPA1 (0.45)	ALOX15CYP3A4CYP2C19TSHRCYP2C9
	SCHEMBL2178750	0.79	KDM4E (0.45)	ALOX15CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL2618834	0.79	KDM4E (0.49)	ALOX15TSHRALDH1A1TDP1MEN1
	SCHEMBL5252344	0.79	KDM4E (0.45)	CYP3A4CYP2D6CYP2C19TSHRHIF1A
	SCHEMBL8712221	0.79	PTGDR2 (0.59)	ALOX15CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL30152364	0.79	PTGDR2 (0.59)	ALOX15CYP3A4CYP2D6CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.