SCHEMBL12840484

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12840367	0.92	TMIGD3 (0.52)	TMIGD3CCNE1CDK2CDK5KMT2A
	SCHEMBL13068291	0.91	TMIGD3 (0.43)	TMIGD3CCNE1CDK2CDK5KMT2A
	SCHEMBL12838582	0.90	ROCK1 (0.42)	TMIGD3CCNE1CDK2KMT2AMEN1
	SCHEMBL12838905	0.90	DEGS1 (0.49)	TMIGD3CCNE1CDK2CDK5KMT2A
	SCHEMBL12838580	0.89	KMT2A (0.47)	KMT2AMEN1NPC1RAB9AWNT3A
	SCHEMBL12838577	0.89	MAPK1 (0.40)	TMIGD3CCNE1CDK2CDK5KMT2A
	SCHEMBL12838584	0.89	RORC (0.45)	CDK2KMT2AMEN1NPC1RAB9A
	SCHEMBL12839214	0.89	TMIGD3 (0.45)	TMIGD3CCNE1CDK2CDK5KMT2A
	SCHEMBL12839167	0.89	MAPK14 (0.48)	TMIGD3CCNE1CDK2CDK5KMT2A
	SCHEMBL12840507	0.89	RIOK2 (0.50)	KMT2AMEN1MAPK8MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.