SCHEMBL12840367

SCHEMBL12840367

CCc1nc(-c2ccccc2)cnc1NC(=O)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TMIGD3 P0DMS9 1/20 0.52
ELOVL1 Q9BW60 1/20 0.50
CCNE1 P24864 4/20 0.49
CDK2 P24941 4/20 0.49
CDK5 Q00535 4/20 0.49
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HSD17B10 Q99714 1/20 0.45
TSHR P16473 1/20 0.45
IKBKB O14920 1/20 0.45
WNT3A P56704 1/20 0.45
PRKACA P17612 1/20 0.44
ROCK1 Q13464 1/20 0.44
GLS O94925 1/20 0.44
RORC P51449 1/20 0.44
DEGS1 O15121 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12839938 0.93 KMT2A (0.48) TMIGD3ELOVL1CCNE1CDK2CDK5
SCHEMBL12838905 0.93 DEGS1 (0.49) TMIGD3ELOVL1CCNE1CDK2CDK5
SCHEMBL12839944 0.92 TMIGD3 (0.45) TMIGD3ELOVL1CCNE1CDK2CDK5
SCHEMBL12839937 0.92 NPC1 (0.48) TMIGD3ELOVL1CCNE1CDK2CDK5
SCHEMBL12840484 0.92 TMIGD3 (0.45) TMIGD3ELOVL1CCNE1CDK2CDK5
SCHEMBL12839932 0.92 KMT2A (0.47) TMIGD3ELOVL1KMT2AMEN1NPC1
SCHEMBL12839167 0.92 MAPK14 (0.48) TMIGD3ELOVL1CCNE1CDK2CDK5
SCHEMBL12838964 0.90 SMN1; SMN2 (0.53) CDK5KMT2AMEN1NPC1RAB9A
SCHEMBL12840353 0.89 RIOK2 (0.54) KMT2AMEN1WNT3A
SCHEMBL12840351 0.88 MAPT (0.47) KMT2AMEN1NPC1RAB9AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110070656-A1 Fluorescent Proteins JNC CORPORATION (JP) 2011-03-24 US disclosed
EP-1666488-B1 FLUORESCENT PROTEIN CHISSO CORP (JP) 2010-11-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110070656-A1 Fluorescent Proteins CACYBP, CHLSN, LCP2 TMIGD3 1782/4885ELOVL1 3538/4885CCNE1 3846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.