Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.49 |
| ▸ | CTSK | P43235 | 15/20 | 0.49 |
| ▸ | CTSB | P07858 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993347 | 1.00 | CTSS (0.49) | CTSSCTSKCTSBCTSLCA1 | |
| SCHEMBL993703 | 0.89 | CA1 (0.53) | CTSSCTSKCTSBCTSLCA1 | |
| SCHEMBL994140 | 0.89 | CA1 (0.53) | CTSSCTSKCTSBCTSLCA1 | |
| SCHEMBL12168586 | 0.89 | CA1 (0.53) | CTSSCTSKCTSBCTSLCA1 | |
| SCHEMBL13015865 | 0.89 | PPARG (0.51) | CTSSCTSKCTSBCTSLCA1 | |
| SCHEMBL13016479 | 0.88 | CTSS (0.63) | CTSSCTSKCTSBCTSLCA1 | |
| SCHEMBL30968897 | 0.87 | CTSS (0.62) | CTSSCTSKCTSBCTSLCA1 | |
| SCHEMBL42634 | 0.87 | CTSS (0.62) | CTSSCTSKCTSBCTSLCA1 | |
| SCHEMBL13583903 | 0.87 | CTSS (0.62) | CTSSCTSKCTSBCTSLCA1 | |
| SCHEMBL9582823 | 0.87 | CTSS (0.62) | CTSSCTSKCTSBCTSLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262764-B1 | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS | UNIV NORTH CAROLINA (US) | 2014-11-12 | — | — | EP | disclosed |
| WO-2011037833-A2 | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-03-31 | — | — | WO | disclosed |
| WO-2010148300-A1 | METHODS OF TREATMENT OF NEUROLOGICAL DISORDERS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-12-23 | — | — | WO | disclosed |