Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.62 |
| ▸ | CTSK | P43235 | 10/20 | 0.62 |
| ▸ | CTSB | P07858 | 4/20 | 0.62 |
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13583903 | 1.00 | CTSS (0.62) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL9582823 | 1.00 | CTSS (0.62) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL30968897 | 1.00 | CTSS (0.62) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL992881 | 0.90 | PSMB1 (0.58) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL18546605 | 0.90 | CTSK (0.64) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL25884513 | 0.90 | CTSK (0.64) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL18546494 | 0.90 | CTSK (0.64) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL3383006 | 0.90 | CTSS (0.77) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL8574604 | 0.88 | CTSS (0.61) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL1290504 | 0.88 | CA12 (0.70) | CTSSCTSKCTSBCTSLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829226-B2 | Lacosamide intermediate compound, preparation method thereof and use thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2014-09-09 | — | — | US | claimed |
| US-20130066102-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2013-03-14 | — | — | US | claimed |
| WO-2013024383-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2013-02-21 | — | — | WO | claimed |
| US-20120283466-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2012-11-08 | — | — | US | claimed |
| US-20110319649-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | EUTICALS GMBH (DE) | 2011-12-29 | — | — | US | claimed |
| EP-2399901-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | Archimica GmbH (DE) | 2011-12-28 | — | — | EP | claimed |
| CN-118271200-A | Industrial preparation method and application of lacosamide | 北京澳合药物研究院有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115616118-B | High performance liquid chromatography for high performance separation and detection of related substances in D-serine | 北京澳合药物研究院有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-115616118-A | High performance liquid chromatography for high performance separation and detection of related substances in D-serine | 北京澳合药物研究院有限公司 | 2023-01-17 | — | — | CN | disclosed |
| EP-3519382-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | UNICHEM LAB LTD (IN) | 2021-10-27 | — | — | EP | disclosed |
| EP-3144295-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | Divi's Laboratories Limited (IN) | 2017-03-22 | — | — | EP | disclosed |
| EP-2444390-B1 | Process for producing Lacosamide | EUTICALS GMBH (DE) | 2017-02-01 | — | — | EP | disclosed |
| US-9447024-B1 | Process for the preparation of lacosamide | DIVI'S LABORATORIES LIMITED (IN) | 2016-09-20 | — | — | US | disclosed |
| WO-2012001710-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | SUN PHARMACEUTICAL INDUSTRIES LTD (IN) | 2012-01-05 | — | — | WO | disclosed |
| US-20110319649-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | EUTICALS GMBH (DE) | 2011-12-29 | — | — | US | disclosed |
| US-20110319649-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | EUTICALS GMBH (DE) | 2011-12-29 | — | — | US | disclosed |
| US-20110319649-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | EUTICALS GMBH (DE) | 2011-12-29 | — | — | US | disclosed |
| EP-2399901-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | Archimica GmbH (DE) | 2011-12-28 | — | — | EP | disclosed |
| WO-2011144983-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |
| CN-102146048-A | Lacosamide intermediate compound and preparation method and application thereof | ZHEJIANG JIUZHOU PHARM CO LTD | 2011-08-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130066102-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | IDH3A, CACNA1C, DDC | CTSS 590/4885CTSK 1040/4885CTSB 640/4885 |
| US-20110319649-A1 | Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide | NAAA, MEP1B, BCHE | CTSS 809/4885CTSK 1129/4885CTSB 445/4885 |
| US-20120283466-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | IDH3A, CACNA1C, DDC | CTSS 590/4885CTSK 1040/4885CTSB 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.