Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993033 | 0.80 | MAOB (0.50) | ACACBSCN9AGRM5MAOBMAOA | |
| SCHEMBL8837185 | 0.72 | CA12 (0.50) | SCN9AKDM4E | |
| SCHEMBL9369401 | 0.64 | CA12 (0.42) | ACACBSCN9AKDM4ERAB9A | |
| SCHEMBL993973 | 0.64 | MAOB (0.52) | ACACBSCN9AGRM5MAOBMAOA | |
| SCHEMBL12840830 | 0.64 | CA12 (0.37) | SCN9A | |
| SCHEMBL1710436 | 0.60 | CCR2 (0.48) | SCN9AGAARAB9A | |
| SCHEMBL994999 | 0.60 | MAOB (0.65) | SCN9AGRM5MAOBMAOA | |
| SCHEMBL993070 | 0.60 | MAOB (0.65) | SCN9AGRM5MAOBMAOA | |
| SCHEMBL993071 | 0.60 | MAOB (0.65) | SCN9AGRM5MAOBMAOA | |
| SCHEMBL7528147 | 0.59 | ANPEP (0.46) | SCN9ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011037833-A2 | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-03-31 | — | — | WO | disclosed |