Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137159 | 0.86 | HPGD (0.43) | ANPEPMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL7526519 | 0.86 | CA12 (0.52) | CYP2C19SRCALDH1A1CA12CA1 | |
| SCHEMBL1710436 | 0.82 | CCR2 (0.48) | ANPEPRAB9AMAPK1CYP2D6CYP2C9 | |
| SCHEMBL7529482 | 0.80 | SLC1A2 (0.45) | CYP2C19FOLH1ALDH1A1HPGD | |
| SCHEMBL14471319 | 0.75 | ANPEP (0.55) | ANPEPRAB9AMAPK1FOLH1SRC | |
| SCHEMBL30006359 | 0.73 | SRC (0.56) | ANPEPRAB9AMAPK1SRCPOLB | |
| SCHEMBL885310 | 0.73 | SRC (0.56) | ANPEPRAB9AMAPK1SRCPOLB | |
| SCHEMBL6813264 | 0.73 | CA12 (0.72) | ANPEPRAB9AMAPK1CYP2D6CYP2C9 | |
| SCHEMBL464926 | 0.73 | CA12 (0.72) | ANPEPRAB9AMAPK1CYP2D6CYP2C9 | |
| SCHEMBL13797510 | 0.72 | ANPEP (0.60) | ANPEPRAB9AMAPK1SRCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378729-A | Diamide derivatives | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-01-03 | — | — | US | claimed |
| EP-0400440-B1 | Amino acid derivative anticonvulsant | RES CORP TECHNOLOGIES INC (US) | 2002-03-13 | — | — | EP | disclosed |
| US-5654301-A | Lacosamide FDA Orange book listed patent | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5378729-A | Diamide derivatives | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1992021648-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-10 | — | — | WO | disclosed |
| WO-1990015069-A2 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-13 | — | — | WO | disclosed |
| EP-0400440-A1 | Amino acid derivative anticonvulsant | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |