Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 5/20 | 1.00 |
| ▸ | SNCA | P37840 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | APEX1 | P27695 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | RAD52 | P43351 | 2/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Epigallocatechin SCHEMBL29870730 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT | |
| Epigallocatechin SCHEMBL1972940 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT | |
| (-)-Gallocatechin SCHEMBL30159803 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT | |
| Epigallocatechin SCHEMBL1972938 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT | |
| Epigallocatechin SCHEMBL12285364 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT | |
| Epigallocatechin SCHEMBL19553 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT | |
| Gallocatechin SCHEMBL3872234 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT | |
| Epigallocatechin SCHEMBL20203645 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT | |
| (-)-Gallocatechin SCHEMBL1742127 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT | |
| Epigallocatechin SCHEMBL29929503 | 1.00 | BACE1 (1.00) | BACE1KDM4EPTGS1SNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292226-A2 | The use of a polyphenol for the treatment of a cancerous or pre-cancerous lesion of the skin | MediGene AG (DE) | 2011-03-09 | — | — | EP | disclosed |