Epigallocatechin

Epigallocatechin

SCHEMBL19553

Oc1cc(O)c2c(c1)O[C@H](c1cc(O)c(O)c(O)c1)[C@H](O)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 6/20 1.00
KDM4E B2RXH2 6/20 1.00
PTGS1 P23219 5/20 1.00
SNCA P37840 4/20 1.00
MAPT P10636 4/20 1.00
APEX1 P27695 4/20 1.00
RECQL P46063 4/20 1.00
HSD17B10 Q99714 4/20 1.00
ALDH1A1 P00352 3/20 1.00
HPGD P15428 3/20 1.00
ALOX15 P16050 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
RAD52 P43351 2/20 1.00
CNR1 P21554 1/20 1.00
MEN1 O00255 4/20 0.74
KMT2A Q03164 4/20 0.74
GAA P10253 3/20 0.74
CYP3A4 P08684 3/20 0.74
PKM P14618 2/20 0.74
PTGS2 P35354 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epigallocatechin SCHEMBL29870730 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT
Epigallocatechin SCHEMBL12840936 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT
Epigallocatechin SCHEMBL1972940 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT
(-)-Gallocatechin SCHEMBL30159803 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT
Epigallocatechin SCHEMBL1972938 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT
Epigallocatechin SCHEMBL12285364 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT
Gallocatechin SCHEMBL3872234 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT
Epigallocatechin SCHEMBL20203645 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT
(-)-Gallocatechin SCHEMBL1742127 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT
Epigallocatechin SCHEMBL29929503 1.00 BACE1 (1.00) BACE1KDM4EPTGS1SNCAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18649 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080093-A Compounds effective in treating liver toxicity and fatty liver disease and uses thereof 2026-05-26 CN claimed
CN-122080155-A Chinese torreya MATE transporter TgMATE, coding gene and application 2026-05-26 CN claimed
US-12636311-B2 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation GALLEON LABS LLC (US) 2026-05-26 US claimed
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
EP-4743071-A2 DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF INNOVENE INC. (US) 2026-05-20 EP claimed
CN-122063058-A Fixation time determining method and related device based on non-volatile compound analysis 贵州大学 2026-05-19 CN claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
WO-2026102239-A1 CRYSTALLINE FORM OF EPIGALLOCATECHIN-3-GALLATE PHARMASSÊTX INC. (US) 2026-05-15 WO claimed
CN-122031747-A Mesoscopic phase enhanced polyphenol-based aggregate adhesive and preparation method thereof 华南理工大学 2026-05-15 CN claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
EP-0417385-A2 Preventive and curative medicament against infection with influenza virus, containing tea or tea polyphenols MITSUI NORIN CO., LTD. (JP) 1991-03-20 EP claimed
EP-0415126-A1 Anti-dental plaque agents MITSUI NORIN CO., LTD. (JP) 1991-03-06 EP claimed
EP-0397914-A1 Antitoxins for bacterial exotoxins MITSUI NORIN CO., LTD. (JP) 1990-11-22 EP claimed
US-4906480-A Sweetness and flavor enhanced compositions and method of preparing such compositions FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) 1990-03-06 US claimed
US-4680193-A Solubilization of tea in cold water with catechin NESTEC S.A. (CH) 1987-07-14 US claimed
EP-0201000-A2 Stabilisation of tea in cold water SOCIETE DES PRODUITS NESTLE S.A. (CH) 1986-11-12 EP claimed
US-4613672-A SOLVENT EXTRACTION MITSU NORIN CO., LTD. (JP) 1986-09-23 US claimed
US-4585738-A FOOD PROCESSING KRAFT, INC. (US) 1986-04-29 US claimed
US-4517175-A FLAVANOL DERIVATIVES AND PROTEINS KAO CORPORATION (JP) 1985-05-14 US claimed
US-4248789-A MIXING CAFFEINE SOLUTION WITH TANNIC SOLUTION EXTRACTED FROM TEA DIRECTOR OF NATIONAL RESEARCH INSTITUTE OF TEA (JP) 1981-02-03 US claimed