Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349728 | 0.86 | KMT2A (0.45) | KMT2AHSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL28288818 | 0.76 | GLA (0.53) | KMT2AHSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL12841647 | 0.75 | KMT2A (1.00) | KMT2AHSD17B10LMNAALDH1A1NPC1 | |
| SCHEMBL21111108 | 0.73 | KMT2A (0.62) | KMT2AKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL8845881 | 0.71 | KMT2A (0.54) | KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL18912121 | 0.71 | HSD11B1 (0.59) | KMT2AHSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL13983998 | 0.70 | BCHE (0.67) | KMT2AHSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL28739190 | 0.70 | ALDH1A1 (0.53) | KMT2AHSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL6598339 | 0.70 | ALDH1A1 (0.42) | KMT2AHSD17B10KDM4EALDH1A1NPC1 | |
| SCHEMBL1544137 | 0.69 | HSD11B1 (0.56) | KMT2AHSD17B10KDM4EALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011035064-A2 | TRIAZOLE CATALYSTS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2011-03-24 | — | — | WO | disclosed |