SCHEMBL128424

SCHEMBL128424

CCn1c2ccccc2c2cc(C=NN(C)c3ccccc3)ccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.64
POLB P06746 4/20 0.64
HTT P42858 3/20 0.64
PKM P14618 1/20 0.64
SRC P12931 4/20 0.62
ALDH1A1 P00352 10/20 0.58
SMN1; SMN2 Q16637 10/20 0.58
MAPT P10636 10/20 0.58
HPGD P15428 9/20 0.58
LMNA P02545 6/20 0.58
HSD17B10 Q99714 2/20 0.58
USP2 O75604 1/20 0.58
TSHR P16473 1/20 0.58
CASP1 P29466 1/20 0.58
MEN1 O00255 10/20 0.56
KMT2A Q03164 10/20 0.56
RCE1 Q9Y256 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1596345 1.00 KDM4E (0.64) KDM4EPOLBHTTPKMSRC
SCHEMBL29438474 1.00 KDM4E (0.64) KDM4EPOLBHTTPKMSRC
SCHEMBL14254905 0.96 KDM4E (0.58) KDM4EPOLBHTTPKMSRC
SCHEMBL14224628 0.91 KDM4E (0.52) KDM4EPOLBHTTPKMSRC
SCHEMBL14283651 0.91 KDM4E (0.59) KDM4EPOLBHTTPKMSRC
SCHEMBL170206 0.89 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL332438 0.89 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL29709939 0.89 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL1702588 0.86 KDM4E (0.63) KDM4EPOLBHTTPKMSRC
SCHEMBL9815537 0.86 KMT2A (0.50) KDM4EPOLBHTTPKMSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7919755-B2 Dendrimer based electro-optic sensor APPLIED RESEARCH AND PHOTONICS, INC. 2011-04-05 US claimed
US-7854505-B2 Passive and active photonic crystal structures and devices THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2010-12-21 US claimed
US-20090323014-A1 PASSIVE AND ACTIVE PHOTONIC CRYSTAL STRUCTURES AND DEVICES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-31 US claimed
EP-1668409-A4 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD UNIV CALIFORNIA (US) 2008-08-27 EP claimed
US-20080128618-A1 Dendrimer Based Electro-Optic Sensor APPLIED RESEARCH AND PHOTONICS, INC. 2008-06-05 US claimed
US-20080099698-A1 Dendrimer Based Terahertz Generator APPLIED RESEARCH AND PHOTONICS, INC. 2008-05-01 US claimed
US-20060255322-A1 Methods and compositions for improved electrophoretic display performance WU ZARNG-ARH G 2006-11-16 US claimed
EP-1668409-A2 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD The Regents of The University of California (US) 2006-06-14 EP claimed
EP-1529242-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER Sipix Imaging, Inc. (US) 2005-05-11 EP claimed
US-6862125-B2 Reversible electro-optic device employing aprotic molten salts and method THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-03-01 US claimed
WO-2004099863-A2 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-11-18 WO claimed
US-20040223207-A1 REVERSIBLE ELECTRO-OPTIC DEVICE EMPLOYING APROTIC MOLTEN SALTS AND METHOD LOS ALAMOS NATIONAL SECUIRTY, LLC 2004-11-11 US claimed
US-20040085619-A1 Novel Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. 2004-05-06 US claimed
WO-2004010206-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER SIPIX IMAGING, INC. (US) 2004-01-29 WO claimed
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 US claimed
US-4535042-A Electrophotographic photosensitive member with electron donor and acceptor layers CANON KABUSHIKI KAISHA, A CORP. OF JAPAN (JP) 1985-08-13 US claimed
US-4454212-A PHENYLHYDRAZONE OF CARBAZOLE ALDEHYDE RICOH COMPANY LIMITED (JP) 1984-06-12 US claimed
US-4365014-A CARBAZOLE HYDRAZONE COMPOUNDS AS CHARGE TRANSPORT MATERIALS RICOH COMPANY, LIMITED (JP) 1982-12-21 US claimed
US-4314016-A Electrophotographic element having a bisazo photoconductor RICOH CO., LTD. (JP) 1982-02-02 US claimed