SCHEMBL14224628

SCHEMBL14224628

CN(/N=C/c1ccc2c(c1)c1ccccc1n2Cn1c2ccccc2c2cc(/C=N/N(C)c3ccccc3)ccc21)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.52
POLB P06746 4/20 0.52
HTT P42858 2/20 0.52
PKM P14618 1/20 0.52
SRC P12931 4/20 0.50
SMN1; SMN2 Q16637 10/20 0.48
MAPT P10636 10/20 0.48
MEN1 O00255 9/20 0.48
KMT2A Q03164 9/20 0.48
HPGD P15428 8/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
ALDH1A1 P00352 9/20 0.47
LMNA P02545 7/20 0.47
ALOX12 P18054 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
USP2 O75604 1/20 0.47
TSHR P16473 1/20 0.47
CASP1 P29466 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1596345 0.91 KDM4E (0.64) KDM4EPOLBHTTPKMSRC
SCHEMBL128424 0.91 KDM4E (0.64) KDM4EPOLBHTTPKMSRC
SCHEMBL29438474 0.91 KDM4E (0.64) KDM4EPOLBHTTPKMSRC
SCHEMBL14254905 0.87 KDM4E (0.58) KDM4EPOLBHTTPKMSRC
SCHEMBL9815537 0.87 KMT2A (0.50) KDM4EPOLBHTTPKMSRC
SCHEMBL14283651 0.82 KDM4E (0.59) KDM4EPOLBHTTPKMSRC
SCHEMBL14252670 0.80 KDM4E (0.41) KDM4EPOLBHTTPKMSRC
SCHEMBL29709939 0.80 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL332438 0.80 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL170206 0.80 KDM4E (0.66) KDM4EPOLBHTTPKMSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7354534-B2 Composition for overcoat layer of organophotoreceptor, organophotoreceptor manufactured by employing the same and the electrophotographic imaging apparatus containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-04-08 US disclosed
US-7229728-B2 Positively-charged electrophotographic organic photoreceptor SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-06-12 US disclosed
US-7172843-B2 Composition for overcoat layer of organophotoreceptor, organophotoreceptor manufactured by employing the same and the electrophotographic imaging apparatus containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-02-06 US disclosed
US-20070026331-A1 Composition for overcoat layer of organophotoreceptor, organophotoreceptor manufactured by employing the same and the electrophotographic imaging apparatus containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-02-01 US disclosed
US-7169519-B2 Double-layered positively-charged organic photoreceptor SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-01-30 US disclosed