Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYCS | P99999 | 4/20 | 0.63 |
| ▸ | TOP1 | P11387 | 4/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687798 | 0.94 | TOP1 (0.61) | CYCSTOP1ABCG2ENPP2KDM4E | |
| SCHEMBL12190736 | 0.84 | TOP1 (0.55) | CYCSTOP1ABCG2ALDH1A1MAPT | |
| SCHEMBL3892703 | 0.83 | ABCG2 (0.71) | CYCSTOP1ABCG2ENPP2TERT | |
| SCHEMBL29583274 | 0.83 | ABCG2 (0.71) | CYCSTOP1ABCG2ENPP2TERT | |
| SCHEMBL28491269 | 0.82 | ABCG2 (0.70) | CYCSTOP1ABCG2ENPP2TERT | |
| SCHEMBL28463987 | 0.82 | ABCG2 (0.70) | CYCSTOP1ABCG2ENPP2TERT | |
| SCHEMBL30872331 | 0.82 | ABCG2 (0.70) | CYCSTOP1ABCG2ENPP2TERT | |
| SCHEMBL28498163 | 0.82 | ABCG2 (0.70) | CYCSTOP1ABCG2ENPP2TERT | |
| SCHEMBL28131499 | 0.82 | ABCG2 (0.70) | CYCSTOP1ABCG2ENPP2TERT | |
| SCHEMBL27255483 | 0.82 | TOP1 (0.67) | CYCSTOP1ABCG2ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110064694-A1 | ANTI-HEPATITIS C ACTIVITY OF MESO-TETRAKIS-PORPHYRIN ANALOGUES | YALE UNIVERSITY (US) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064694-A1 | ANTI-HEPATITIS C ACTIVITY OF MESO-TETRAKIS-PORPHYRIN ANALOGUES | HAVCR2, HCCS, HMBS | CYCS 33/4885TOP1 2148/4885ABCG2 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.