Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 11/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 11/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 10/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027805 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1NPC1RAB9APLAAT5 | |
| SCHEMBL13876768 | 0.80 | ALDH1A1 (0.78) | SMN1; SMN2ALDH1A1NPC1RAB9APLAAT5 | |
| SCHEMBL2078764 | 0.79 | POLB (0.61) | SMN1; SMN2ALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL105520 | 0.78 | KDM4E (0.71) | SMN1; SMN2ALDH1A1NPC1RAB9APLAAT5 | |
| SCHEMBL3279011 | 0.77 | MTNR1B (0.71) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL554715 | 0.77 | KMT2A (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL15359146 | 0.76 | ESRRG (0.54) | SMN1; SMN2ALDH1A1NPC1RAB9APLAAT5 | |
| SCHEMBL13808732 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1NPC1RAB9APLAAT5 | |
| SCHEMBL18533665 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1NPC1RAB9APLAAT5 | |
| SCHEMBL15492835 | 0.76 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9APLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110060113-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060113-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | PPARG, PTGER4, NR2E3 | SMN1; SMN2 1801/4885ALDH1A1 330/4885NPC1 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.