Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10190443 | 0.90 | DPP4 (0.51) | DPP4KMT2A | |
| SCHEMBL13876139 | 0.85 | HTR3A (0.39) | DPP4ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3880948 | 0.84 | DPP4 (0.45) | DPP4 | |
| SCHEMBL13876133 | 0.84 | DPP4 (0.57) | DPP4CYP3A4KMT2A | |
| SCHEMBL10244864 | 0.82 | DPP4 (0.49) | DPP4CYP3A4 | |
| SCHEMBL10219640 | 0.78 | DPP4 (0.44) | DPP4L3MBTL1ALDH1A1 | |
| SCHEMBL13866920 | 0.77 | DPP4 (0.48) | DPP4 | |
| SCHEMBL10222244 | 0.76 | DPP4 (0.43) | DPP4L3MBTL1ALDH1A1 | |
| SCHEMBL13867042 | 0.74 | DPP4 (0.56) | DPP4KMT2A | |
| SCHEMBL5640697 | 0.72 | DPP4 (0.58) | DPP4L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |