Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876318 | 0.86 | DPP4 (0.51) | DPP4CYP3A4GRIN1GRIN2BTNKS | |
| SCHEMBL12845233 | 0.82 | DPP4 (0.51) | DPP4CYP3A4 | |
| SCHEMBL10190443 | 0.79 | DPP4 (0.51) | DPP4 | |
| SCHEMBL13875682 | 0.78 | TLR7 (0.39) | — | |
| SCHEMBL13876308 | 0.76 | TLR7 (0.42) | — | |
| SCHEMBL13875752 | 0.75 | HTR2C (0.43) | DPP4CYP3A4 | |
| SCHEMBL13876124 | 0.74 | HTR3A (0.37) | — | |
| SCHEMBL13875683 | 0.74 | SLC2A1 (0.53) | CYP3A4 | |
| SCHEMBL13875864 | 0.74 | TLR7 (0.49) | — | |
| Trifluoroacetic Acid SCHEMBL3880948 | 0.74 | DPP4 (0.45) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040897-A1 | NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040897-A1 | NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES | NR1D2, STARD10, NR1D1 | DPP4 3186/4885CYP3A4 54/4885GRIN1 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.