SCHEMBL128456

SCHEMBL128456

CCCCCCCCc1cc(C(=O)O)c(C)c(C)c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
GABRA4 P48169 1/20 0.48
GABRE P78334 1/20 0.48
GABRA6 Q16445 1/20 0.48
GABRG1 Q8N1C3 1/20 0.48
GABRG3 Q99928 1/20 0.48
GABRQ Q9UN88 1/20 0.48
KAT8 Q9H7Z6 4/20 0.46
PPARA Q07869 3/20 0.46
RARB P10826 3/20 0.45
PPARG P37231 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245179 0.98 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8770841 0.88 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL499086 0.82 KDM4E (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL5136122 0.82 KAT8 (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL5342905 0.82 KAT8 (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL14352830 0.81 KAT8 (0.48) KAT8PPARARARBPPARGBID
SCHEMBL10799505 0.81 KDM4E (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11800974 0.80 KAT8 (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10626153 0.80 KAT8 (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL22773393 0.80 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2897 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014066-A1 Silk-Based Moisturizer Compositions and Methods Thereof EVOLVED BY NATURE INC (US) 2026-01-15 US claimed
EP-4543424-A2 TOPICAL NAFTIFINE COMPOSITIONS Taro Pharmaceutical Industries Ltd. (IL) 2025-04-30 EP claimed
US-20250107974-A1 MICROCAPSULES COMPRISING SUNSCREEN AGENTS TAGRA BIOTECHNOLOGIES LTD. (IL) 2025-04-03 US claimed
CN-119654144-A Topical naftifine compositions 塔罗制药工业有限公司 2025-03-18 CN claimed
US-11878070-B2 Silk-based moisturizer compositions and methods thereof EVOLVED BY NATURE, INC. (US) 2024-01-23 US claimed
WO-2024002698-A1 COSMETIC COMPOSITION OF LIQUID CRYSTAL LIPID PARTICLES FOR IMPROVED ANTIOXIDANT EFFECTS BASF SE (DE) 2024-01-04 WO claimed
WO-2023250369-A2 TOPICAL NAFTIFINE COMPOSITIONS TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) 2023-12-28 WO claimed
EP-3188708-B1 MINERAL SUNSCREEN COMPOSITIONS EDGEWELL PERSONAL CARE BRANDS LLC (US) 2023-05-03 EP claimed
US-11485908-B2 Quantum dot light-emitting diode and method for fabricating the same TCL TECHNOLOGY GROUP CORPORATION (CN) 2022-11-01 US claimed
CN-114886796-A Silk-based moisturizer composition and method thereof 丝绸医疗公司 2022-08-12 CN claimed
EP-0313305-A2 Photoprotection compositions comprising chelating agents THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
EP-0313303-A2 Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
US-4810490-A CLEAR, WATERPROOF FILMS CARTER-WALLACE, INC. (US) 1989-03-07 US claimed
EP-0283165-A2 Skin conditioning composition and method THE PROCTER & GAMBLE COMPANY (US) 1988-09-21 EP claimed
US-4663157-A ACRYLIC ACID-ETHYLENE COPOLYMER THE PROCTOR & GAMBLE COMPANY (US) 1987-05-05 US claimed
EP-0193387-A2 Sunscreen compositions and method of protecting skin THE PROCTER & GAMBLE COMPANY (US) 1986-09-03 EP claimed
US-4563346-A SUNSCREEN AGENTS, TOILETRIES CHARLES OF THE RITZ GROUP LTD. (US) 1986-01-07 US claimed
US-4559225-A CELLULOSE ETHER AND ULTRAVIOLET ABSORBER IN EMOLLIENT JPMORGAN CHASE BANK, AS ADMINISTRATIVE AGENT 1985-12-17 US claimed
EP-0158412-A2 Sunscreen compositions Fourman, Robert Gene (US) 1985-10-16 EP claimed
US-4481186-A SKIN CONDITIONERS CHARLES OF THE RITZ GROUP LTD. (US) 1984-11-06 US claimed