Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284639 | 1.00 | MAPT (0.58) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL30377588 | 0.81 | MAPT (0.63) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL1404944 | 0.81 | MAPT (0.63) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL31356854 | 0.81 | MAPT (0.63) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL1404946 | 0.81 | MAPT (0.63) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL1219446 | 0.80 | MAPT (0.54) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL15081581 | 0.79 | HDAC1 (0.57) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL10781980 | 0.79 | MAPT (0.47) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL481451 | 0.79 | MAPT (0.65) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL165227 | 0.79 | MAPT (0.65) | MAPTALDH1A1KDM4EL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443099-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20120088664-A1 | Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
| WO-2010146113-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
| US-5057532-A | Fungicides, plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |
| EP-0390022-A2 | Azolyl ethyl cyclopropanes, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1990-10-03 | — | — | EP | disclosed |
| EP-0062772-A2 | Regioselective preparation of triazolylvinyl ketones and the intermediates therefor | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088664-A1 | Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent | STS, TST, ERG28 | MAPT 2572/4885ALDH1A1 1568/4885KDM4E 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.