Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 10/20 | 0.65 |
| ▸ | TAS1R1 | Q7RTX1 | 10/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | OXTR | P30559 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310947 | 0.88 | TAS1R3 (0.59) | TAS1R3TAS1R1TRPM8KDM4EALDH1A1 | |
| SCHEMBL31060243 | 0.85 | FLT3 (0.71) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL17541455 | 0.85 | TAS1R3 (0.59) | TAS1R3TAS1R1MAOBTRPM8HDAC3 | |
| SCHEMBL24522315 | 0.84 | TAS1R3 (0.73) | TAS1R3TAS1R1KDM4EALDH1A1HPGD | |
| SCHEMBL29362997 | 0.84 | TAS1R3 (0.73) | TAS1R3TAS1R1KDM4EALDH1A1HPGD | |
| SCHEMBL9612676 | 0.84 | TAS1R3 (0.55) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL1287553 | 0.84 | KDM4E (0.66) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL29527237 | 0.84 | KDM4E (0.66) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL335319 | 0.84 | KDM4E (0.66) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL5806070 | 0.84 | TAS1R3 (0.62) | TAS1R3TAS1R1KDM4EALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065767-A1 | Substituted CC-1065 Analogs and Their Conjugates | SYNTARGA B.V. (NL) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065767-A1 | Substituted CC-1065 Analogs and Their Conjugates | PCNA, TOP1, TOP2B | TAS1R3 4765/4885TAS1R1 4726/4885MAOB 3498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.