Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12596874 | 0.83 | KDM4E (0.77) | ALDH1A1KDM4EHPGDLMNAP4HB | |
| SCHEMBL1771123 | 0.83 | HPGD (1.00) | ALDH1A1KDM4EHPGDLMNAP4HB | |
| SCHEMBL30503469 | 0.82 | KDM4E (0.75) | ALDH1A1KDM4EHPGDLMNAP4HB | |
| Hydrochloric Acid SCHEMBL3555727 | 0.82 | HPGD (0.97) | ALDH1A1KDM4EHPGDLMNAP4HB | |
| SCHEMBL28941241 | 0.82 | KDM4E (0.75) | ALDH1A1KDM4EHPGDLMNAP4HB | |
| SCHEMBL2908238 | 0.82 | KDM4E (0.75) | ALDH1A1KDM4EHPGDLMNAP4HB | |
| SCHEMBL3555723 | 0.82 | HPGD (0.75) | ALDH1A1KDM4EHPGDLMNAP4HB | |
| SCHEMBL18595553 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDLMNAP4HB | |
| SCHEMBL12392288 | 0.79 | KDM4E (0.71) | ALDH1A1KDM4EHPGDLMNAP4HB | |
| SCHEMBL2906697 | 0.77 | KDM4E (0.68) | ALDH1A1KDM4EHPGDLMNAP4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065767-A1 | Substituted CC-1065 Analogs and Their Conjugates | SYNTARGA B.V. (NL) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065767-A1 | Substituted CC-1065 Analogs and Their Conjugates | PCNA, TOP1, TOP2B | ALDH1A1 2231/4885KDM4E 752/4885HPGD 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.