Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022155 | 0.80 | PTGS1 (0.45) | BCHEMAPTGAAMAOAPTGS1 | |
| SCHEMBL29830704 | 0.80 | PTGS1 (0.45) | BCHEMAPTGAAMAOAPTGS1 | |
| SCHEMBL29127386 | 0.71 | KDM1A (0.46) | BCHEMAPTNPSR1MAOAPTGS1 | |
| SCHEMBL12386881 | 0.71 | PTGS1 (0.51) | BCHEMAPTGAAMAOAPTGS1 | |
| SCHEMBL29022142 | 0.70 | BCHE (0.38) | BCHEMAPTMAOAPTGS1PTGS2 | |
| SCHEMBL29831126 | 0.70 | BCHE (0.38) | BCHEMAPTMAOAPTGS1PTGS2 | |
| SCHEMBL4595129 | 0.69 | MAOA (0.48) | BCHEMAPTGAAMAOAPTGS1 | |
| SCHEMBL20348949 | 0.68 | BCHE (0.45) | BCHEMAPTGAANPSR1MAOA | |
| SCHEMBL13485697 | 0.67 | CYP2D6 (0.53) | BCHEMAPTNPSR1MAOAPTGS1 | |
| SCHEMBL627482 | 0.66 | MAOA (0.58) | BCHEMAPTMAOAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897311-B2 | Phenothiazine containing photogenerating layer photoconductors | XEROX CORPORATION (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090274969-A1 | PHENOTHIAZINE CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-11-05 | — | — | US | disclosed |