Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.36 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | CTSB | P07858 | 5/20 | 0.34 |
| ▸ | CTSH | P09668 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911353 | 1.00 | CTSK (0.36) | CTSKCTSLCTSBCTSHCYP1A2 | |
| SCHEMBL13908677 | 0.89 | — | — | |
| SCHEMBL3155857 | 0.81 | CYP1A2 (0.40) | CTSKCTSLCTSBCTSHCYP1A2 | |
| SCHEMBL8605603 | 0.81 | CTSK (0.38) | CTSKCTSLCTSBCTSH | |
| SCHEMBL16824140 | 0.80 | CTSK (0.33) | CTSKCTSLCTSBCTSHCYP1A2 | |
| SCHEMBL1911130 | 0.79 | CYP1A2 (0.34) | CTSKCTSLCTSBCTSHCYP1A2 | |
| SCHEMBL13889045 | 0.79 | CYP1A2 (0.34) | CTSKCTSLCTSBCTSHCYP1A2 | |
| SCHEMBL13002262 | 0.78 | PRMT5 (0.33) | — | |
| SCHEMBL90350 | 0.77 | DPP4 (0.36) | CTSK | |
| SCHEMBL90271 | 0.77 | DPP4 (0.36) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012167309-A1 | MACROMOLECULES | STARPHARMA PTY LTD (AU) | 2012-12-13 | — | — | WO | disclosed |
| US-7906520-B2 | Reducing expression of tetrahydrobiopterin (BH4) biological activity; traumatic, metabolic or toxic peripheral nerve lesions | THE GENERAL HOSPITAL CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |