Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564440 | 0.72 | PLAUR (0.39) | CDC25BPTPRCMAPTNPC1RAB9A | |
| SCHEMBL7534819 | 0.70 | MKNK1 (0.45) | MAPTLMNASMN1; SMN2KMT2ABTK | |
| SCHEMBL12849812 | 0.69 | ALDH1A1 (0.35) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL8564127 | 0.69 | KMT2A (0.39) | CDC25BMAPTNPC1RAB9ACASP3 | |
| SCHEMBL3513772 | 0.69 | MEN1 (0.46) | LMNASMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL30454073 | 0.69 | MEN1 (0.46) | LMNASMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL3943393 | 0.67 | MAPT (0.46) | CDC25BMAPTNPC1RAB9ACASP3 | |
| SCHEMBL8569652 | 0.65 | PTGS2 (0.36) | MAPTNPC1RAB9ACASP3SENP7 | |
| SCHEMBL3232011 | 0.64 | POLB (0.46) | MAPTNPC1RAB9ANFKB1LMNA | |
| SCHEMBL27761013 | 0.63 | NPC1 (0.50) | S100A4CDC25BMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034051-A1 | NOVEL CYCLIC SQUARAMIDE DERIVATIVES | 参天製薬株式会社 (JP) | 2011-03-24 | — | — | WO | disclosed |