Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 8/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285011 | 1.00 | AKR1B10 (0.45) | AKR1B10AKR1B1KMT2ANPC1RAB9A | |
| SCHEMBL1284937 | 0.89 | AGXT (0.40) | AKR1B10AKR1B1KMT2ANPC1RAB9A | |
| SCHEMBL1284938 | 0.89 | AGXT (0.40) | AKR1B10AKR1B1KMT2ANPC1RAB9A | |
| SCHEMBL1284729 | 0.88 | MAPT (0.53) | KMT2ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL1284730 | 0.88 | MAPT (0.53) | KMT2ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL1284893 | 0.87 | NPC1 (0.57) | AKR1B10AKR1B1KMT2ANPC1RAB9A | |
| SCHEMBL1284891 | 0.87 | NPC1 (0.57) | AKR1B10AKR1B1KMT2ANPC1RAB9A | |
| SCHEMBL1285467 | 0.87 | MAPT (0.40) | AKR1B10AKR1B1KMT2ARAB9AMAPT | |
| SCHEMBL1284660 | 0.87 | MAOB (0.40) | AKR1B10AKR1B1KMT2AKDM4EMEN1 | |
| SCHEMBL1285390 | 0.87 | CA12 (0.39) | AKR1B10AKR1B1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383843-B2 | Method for preparing a coumarin compound, chromene compound, and method for preparing a chromene compound | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | CYP3A7, CYP2A7, F7 | AKR1B10 118/4885AKR1B1 188/4885KMT2A 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.