⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129808 | 0.81 | ALDH1A1 (0.48) | — | |
| SCHEMBL11041394 | 0.79 | MEN1 (0.34) | — | |
| SCHEMBL2907462 | 0.78 | MMP1 (0.42) | — | |
| SCHEMBL11473185 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL10900063 | 0.75 | ESR1 (0.32) | — | |
| SCHEMBL4839246 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL21488619 | 0.72 | SOAT1 (0.33) | — | |
| SCHEMBL28243943 | 0.71 | TDP1 (0.38) | — | |
| SCHEMBL2901049 | 0.71 | ALDH1A1 (0.52) | — | |
| SCHEMBL126951 | 0.71 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-112424181-A | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2021-02-26 | — | — | CN | claimed |
| US-8658639-B2 | N-substituted-cyclic amino derivative | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-02-25 | — | — | US | claimed |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-17 | — | — | US | claimed |
| EP-2447264-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-05-02 | — | — | EP | claimed |
| US-7452875-B2 | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-11-18 | — | — | US | claimed |
| US-7427611-B2 | Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-09-23 | — | — | US | claimed |
| US-7410962-B2 | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-08-12 | — | — | US | claimed |
| US-20080085889-A1 | Amidomethyl-Substituted 1-(Carboxyalkyl) Cyclopentyl-Carbonylamino-Benzazepine-N-Acetic Acid Compounds, Process and Intermediate Products for Their Preparation and Pharmaceutical Compositions Containing Them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-04-10 | — | — | US | claimed |
| US-20070265244-A1 | AMIDOMETHYL-SUBSTITUTED 1-(CARBOXYALKYL) CYCLOPENTYL-CARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID COMPOUNDS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-15 | — | — | US | claimed |
| WO-1991008195-A1 | N-(1-(2-CARBOXYETHYL)CYCLOALKYL CARBONYL)-BETA-ALANINE DERIVATIVES FOR PHARMACEUTICAL USE | PFIZER LIMITED (GB) | 1991-06-13 | — | — | WO | claimed |
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | claimed |
| EP-0358398-A1 | Cycloalkyl-substituted glutaramide antihypertensive agents | Pfizer Limited (GB) | 1990-03-14 | — | — | EP | claimed |
| CN-1038096-A | Application with the compound of treatment psychosis effect, the reagent that contains this compounds and treatment thereof and prevention central nervous system disorder | HOECHST AG (DE) | 1989-12-20 | — | — | CN | claimed |
| EP-0343911-A2 | Cycloalkyl-substituted glutaramide diuretic agents | Pfizer Limited (GB) | 1989-11-29 | — | — | EP | claimed |
| EP-0342850-A1 | Enantiomeric glutaramide diuretic agents | Pfizer Limited (GB) | 1989-11-23 | — | — | EP | claimed |
| EP-0331609-A2 | Angiotensin converting enzyme inhibitors having psychotropic effects | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-06 | — | — | EP | claimed |
| EP-0326974-A1 | Amino acid amides with a psychotropic activity, processes for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-09 | — | — | EP | claimed |
| EP-0274234-A2 | Spiro-subsituted glutaramide diuretic agents | Pfizer Limited (GB) | 1988-07-13 | — | — | EP | claimed |
| US-4563446-A | ANTICOAGULANT, ANTISCHEMIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-01-07 | — | — | US | claimed |