⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448323 | 0.84 | — | — | |
| SCHEMBL16752678 | 0.84 | L3MBTL1 (0.36) | — | |
| SCHEMBL13411814 | 0.84 | L3MBTL1 (0.36) | — | |
| SCHEMBL10641491 | 0.84 | L3MBTL1 (0.36) | — | |
| SCHEMBL16752719 | 0.84 | L3MBTL1 (0.36) | — | |
| SCHEMBL2979571 | 0.79 | HIF1A (0.33) | — | |
| SCHEMBL5546668 | 0.79 | — | — | |
| SCHEMBL1286520 | 0.79 | L3MBTL1 (0.30) | — | |
| SCHEMBL4684913 | 0.79 | L3MBTL1 (0.30) | — | |
| SCHEMBL3872946 | 0.77 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765408-B1 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK AS (DK) | 2015-12-09 | — | — | EP | claimed |
| US-9061067-B2 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2015-06-23 | — | — | US | claimed |
| EP-2289560-B1 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK AS (DK) | 2015-04-22 | — | — | EP | claimed |
| US-20120088716-A1 | Polypeptide Protracting Tags | NOVO NORDISK A/S (DK) | 2012-04-12 | — | — | US | claimed |
| EP-2292272-A2 | Polypeptide protracting tags comprising a tetrazole moiety | NOVO NORDISK A/S (DK) | 2011-03-09 | — | — | EP | claimed |
| EP-2289560-A2 | Polypeptide protracting tags comprising a tetrazole moiety | NOVO NORDISK A/S (DK) | 2011-03-02 | — | — | EP | claimed |
| US-20090111730-A1 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2009-04-30 | — | — | US | claimed |
| EP-1765408-A2 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK A/S (DK) | 2007-03-28 | — | — | EP | claimed |
| WO-2006005667-A2 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK A/S (DK) | 2006-01-19 | — | — | WO | claimed |
| EP-1765408-B1 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK AS (DK) | 2015-12-09 | — | — | EP | disclosed |
| US-9061067-B2 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2015-06-23 | — | — | US | disclosed |
| EP-2289560-B1 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK AS (DK) | 2015-04-22 | — | — | EP | disclosed |
| US-20120088716-A1 | Polypeptide Protracting Tags | NOVO NORDISK A/S (DK) | 2012-04-12 | — | — | US | disclosed |
| EP-2292272-A2 | Polypeptide protracting tags comprising a tetrazole moiety | NOVO NORDISK A/S (DK) | 2011-03-09 | — | — | EP | disclosed |
| EP-2289560-A2 | Polypeptide protracting tags comprising a tetrazole moiety | NOVO NORDISK A/S (DK) | 2011-03-02 | — | — | EP | disclosed |
| US-20090111730-A1 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2009-04-30 | — | — | US | disclosed |
| EP-1765408-A2 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK A/S (DK) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005667-A2 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK A/S (DK) | 2006-01-19 | — | — | WO | disclosed |