Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.32 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285239 | 1.00 | KDM4E (0.36) | KDM4ESMN1; SMN2HSD17B10MMP2MMP9 | |
| SCHEMBL1285424 | 0.93 | MAOA (0.34) | KDM4ESMN1; SMN2HSD17B10MMP2MMP9 | |
| SCHEMBL1285425 | 0.93 | MAOA (0.34) | KDM4ESMN1; SMN2HSD17B10MMP2MMP9 | |
| SCHEMBL1285404 | 0.93 | KDM4E (0.39) | KDM4ESMN1; SMN2HSD17B10MMP2MMP9 | |
| SCHEMBL1285402 | 0.93 | KDM4E (0.39) | KDM4ESMN1; SMN2HSD17B10MMP2MMP9 | |
| SCHEMBL1285742 | 0.91 | MAOA (0.36) | SMN1; SMN2MMP2MMP9ADAM17MAOB | |
| SCHEMBL1285743 | 0.91 | MAOA (0.36) | SMN1; SMN2MMP2MMP9ADAM17MAOB | |
| SCHEMBL1284458 | 0.90 | TP53 (0.37) | KDM4ESMN1; SMN2HSD17B10MMP2MMP9 | |
| SCHEMBL1284459 | 0.90 | TP53 (0.37) | KDM4ESMN1; SMN2HSD17B10MMP2MMP9 | |
| SCHEMBL1284818 | 0.89 | KDM4E (0.36) | KDM4ESMN1; SMN2HSD17B10MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383843-B2 | Method for preparing a coumarin compound, chromene compound, and method for preparing a chromene compound | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | CYP3A7, CYP2A7, F7 | KDM4E 3026/4885SMN1; SMN2 4471/4885HSD17B10 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.