Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16206231 | 0.83 | GBA1 (0.60) | MAOBCYP19A1MAOAGBA1HRH4 | |
| SCHEMBL27777026 | 0.83 | GBA1 (0.57) | MAOBCYP19A1MAOAGBA1HRH4 | |
| SCHEMBL15014123 | 0.83 | CYP19A1 (0.76) | MAOBCYP19A1MAOAHRH4NPC1 | |
| SCHEMBL16903654 | 0.83 | MAOB (0.55) | MAOBCYP19A1MAOAGBA1HRH4 | |
| SCHEMBL15836589 | 0.80 | CYP19A1 (0.72) | MAOBCYP19A1MAOAGBA1HRH4 | |
| SCHEMBL16906517 | 0.79 | MAOB (0.51) | MAOBCYP19A1MAOAGBA1HRH4 | |
| SCHEMBL16401668 | 0.79 | GBA1 (0.52) | MAOBCYP19A1MAOAGBA1HRH4 | |
| SCHEMBL31415830 | 0.79 | CYP19A1 (0.50) | MAOBCYP19A1MAOAGBA1HRH4 | |
| SCHEMBL16092964 | 0.78 | MAPT (0.49) | CYP19A1MAOAHRH3 | |
| SCHEMBL13074186 | 0.78 | CYP19A1 (0.64) | MAOBCYP19A1MAOAGBA1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447103-B2 | Inauhzin analogues that induce P53, inhibit cell growth, and have antitumor activity | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2016-09-20 | — | — | US | disclosed |
| US-20150197522-A1 | INAUHZIN ANALOGUES THAT INDUCE P53, INHIBIT CELL GROWTH, AND HAVE ANTITUMOR ACTIVITY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (US) | 2015-07-16 | — | — | US | disclosed |
| US-8470985-B2 | Triazole compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-8278281-B2 | Triazole compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100016955-A1 | Triazole compounds and methods of making and using the same | BioVersys AG (CH) | 2010-01-21 | — | — | US | disclosed |
| US-20100016956-A1 | Triazole compounds and methods of making and using the same | BioVersys AG (CH) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016956-A1 | Triazole compounds and methods of making and using the same | IL33, PROKR1, PGC | MAOB 1477/4885CYP19A1 2156/4885MAOA 1668/4885 |
| US-20100016955-A1 | Triazole compounds and methods of making and using the same | IL33, PROKR1, VIP | MAOB 1760/4885CYP19A1 2296/4885MAOA 1972/4885 |
| US-20150197522-A1 | INAUHZIN ANALOGUES THAT INDUCE P53, INHIBIT CELL GROWTH, AND HAVE ANTITUMOR ACTIVITY | TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NOP58 | MAOB 4665/4885CYP19A1 4127/4885MAOA 4051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.