Ampyrone

Ampyrone

SCHEMBL128544

Cc1c(N)c(=O)n(-c2ccccc2)n1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 1.00
PTGS2 P35354 1/20 1.00
ALOX15 P16050 2/20 0.64
ALDH1A1 P00352 2/20 0.64
LMNA P02545 2/20 0.62
ADORA3 P0DMS8 1/20 0.62
TSHR P16473 3/20 0.60
CYP1A2 P05177 2/20 0.60
THRB P10828 2/20 0.60
NAPRT Q6XQN6 1/20 0.60
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 4/20 0.56
CYP2D6 P10635 1/20 0.55
POLB P06746 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.51
MAPT P10636 3/20 0.51
TP53 P04637 1/20 0.51
HSP90AA1 P07900 1/20 0.51
HSP90AB1 P08238 1/20 0.51
MAPK1 P28482 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ampyrone SCHEMBL18159502 1.00 BCHE (1.00) BCHEPTGS2ALOX15ALDH1A1LMNA
Ampyrone SCHEMBL11674586 1.00 BCHE (1.00) BCHEPTGS2ALOX15ALDH1A1LMNA
Ampyrone SCHEMBL1830291 0.98 BCHE (0.96) BCHEPTGS2ALOX15ALDH1A1LMNA
Ampyrone SCHEMBL10746988 0.98 BCHE (0.96) BCHEPTGS2ALOX15ALDH1A1LMNA
Ampyrone SCHEMBL28606780 0.92 BCHE (0.84) BCHEPTGS2ALOX15ALDH1A1LMNA
Ampyrone SCHEMBL3092850 0.92 BCHE (0.84) BCHEPTGS2ALOX15ALDH1A1LMNA
Ampyrone SCHEMBL10711697 0.91 BCHE (0.82) BCHEPTGS2ALOX15ALDH1A1LMNA
Ampyrone SCHEMBL4542675 0.89 BCHE (0.79) BCHEPTGS2ALOX15ALDH1A1LMNA
Ampyrone SCHEMBL28982549 0.89 BCHE (0.79) BCHEPTGS2ALOX15ALDH1A1LMNA
Ampyrone SCHEMBL8624284 0.89 BCHE (0.79) BCHEPTGS2ALOX15ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15519 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081442-A Fingertip peripheral blood lipid multi-index synchronous analysis method and system 2026-05-26 CN claimed
CN-122072231-A Uric acid colorimetric detection method and application thereof 天津科技大学 2026-05-22 CN claimed
CN-118406492-B Preparation method and application of metal doped carbon dots 北京师范大学 2026-05-15 CN claimed
CN-122017217-A One-card-three-way dry chemical detection reagent strip, detection system and method 天津师范大学 2026-05-12 CN claimed
CN-122016686-A Method for quickly detecting sodium dehydroacetate in colorimetric/fluorescent dual-mode by using peroxidase-like laccase nano-enzyme 云南伦扬科技有限公司 2026-05-12 CN claimed
US-20260114758-A1 PAPER-BASED WEARABLE PATCHES FOR REAL-TIME, QUANTITATIVE LACTATE MONITORING Trustees of Tuffs College (US) 2026-04-30 US claimed
EP-4361631-B1 COLOROMETRIC SENSOR FOR THE NON-INVASIVE SCREENING OF GLUCOSE IN SWEAT IN PRE AND TYPE 2 DIABETES MEDTRONIC MINIMED INC (US) 2026-04-15 EP claimed
EP-4720318-A1 METHODS AND COMPOSITIONS FOR THE PRODUCTION OF GLYOXAL Solugen, Inc. (US) 2026-04-08 EP claimed
US-20260092336-A1 AMPLICON-DEPLETED CRISPR/CAS-REGULATED ISOTHERMAL MOLECULAR ASSAY AT SKIN TEMPERATURE ENABLING MULTI-LEVEL, EQUIPMENT-FREE, HOME-BASED SELF-TESTING OF VIRAL INFECTIONS UNIV HONG KONG SCIENCE & TECH (CN) 2026-04-02 US claimed
US-20260083666-A1 METHOD OF TREATING DISEASE CREWS THOMAS M (US) 2026-03-26 US claimed
US-4184921-A Process and reagent for determining cholesterol BOEHRINGER MANNHEIM GMBH (DE) 1980-01-22 US claimed
US-4135980-A PREPARATION BY CULTURING MICROORGANISM OF GENUS ARTHROBACTER, USE IN DETERMINATION OF CHOLINE OR BETAINE ALDEHYDE TOYO JOZO KABUSHIKI KAISHA (JP) 1979-01-23 US claimed
US-4098574-A BUFFERED TRINDER'S REAGENT EASTMAN KODAK COMPANY (US) 1978-07-04 US claimed
US-4073701-A ACETANILIDE OXIDATION INHIBITING AGENT BETHLEHEM STEEL CORPORATION (US) 1978-02-14 US claimed
US-RE29498-E PEROXIDASE ENZYME SYSTEM Istituto Sieroterapico e Vaccinogeno Toscano "SCLAVO", S.p.A. (IT) 1977-12-20 US claimed
US-4040787-A THIOSEMICARBAZIDE, 4-AMINO-ANTIPYRINE THE DOW CHEMICAL COMPANY (US) 1977-08-09 US claimed
US-3992158-A Integral analytical element EASTMAN KODAK COMPANY (US) 1976-11-16 US claimed
US-3988430-A ANTIGENS HOFFMANN-LA ROCHE INC. (US) 1976-10-26 US claimed
US-3983005-A Integral element for the analysis of cholesterol EASTMAN KODAK COMPANY (US) 1976-09-28 US claimed
US-3955928-A Pregnancy test YEE HUGH 1976-05-11 US claimed