Ampyrone

Ampyrone

SCHEMBL3092850

Cc1c(N)c(=O)n(-c2ccccc2)n1C.Oc1ccccc1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.84
PTGS2 P35354 1/20 0.84
ALDH1A1 P00352 2/20 0.64
ALOX15 P16050 2/20 0.64
L3MBTL1 Q9Y468 1/20 0.57
MAOB P27338 1/20 0.54
LMNA P02545 3/20 0.54
ADORA3 P0DMS8 1/20 0.54
KDM4E B2RXH2 3/20 0.54
TSHR P16473 3/20 0.53
CYP1A2 P05177 2/20 0.53
THRB P10828 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
MAPT P10636 3/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
CYP2D6 P10635 1/20 0.49
GAA P10253 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ampyrone SCHEMBL11674586 0.92 BCHE (1.00) BCHEPTGS2ALDH1A1ALOX15LMNA
Ampyrone SCHEMBL128544 0.92 BCHE (1.00) BCHEPTGS2ALDH1A1ALOX15LMNA
Ampyrone SCHEMBL18159502 0.92 BCHE (1.00) BCHEPTGS2ALDH1A1ALOX15LMNA
Ampyrone SCHEMBL1830291 0.90 BCHE (0.96) BCHEPTGS2ALDH1A1ALOX15LMNA
Ampyrone SCHEMBL10746988 0.90 BCHE (0.96) BCHEPTGS2ALDH1A1ALOX15LMNA
Ampyrone SCHEMBL15971631 0.89 BCHE (0.71) BCHEPTGS2ALDH1A1ALOX15L3MBTL1
Ampyrone SCHEMBL28606780 0.88 BCHE (0.84) BCHEPTGS2ALDH1A1ALOX15LMNA
Ampyrone SCHEMBL8822010 0.87 BCHE (0.68) BCHEPTGS2ALDH1A1ALOX15L3MBTL1
Ampyrone SCHEMBL28982549 0.85 BCHE (0.79) BCHEPTGS2ALDH1A1ALOX15LMNA
Ampyrone SCHEMBL8624284 0.85 BCHE (0.79) BCHEPTGS2ALDH1A1ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0285998-A2 Method and reagent for determination of dehydrogenase or its substrate TOYO BOSEKI KABUSHIKI KAISHA (JP) 1988-10-12 EP claimed
US-4503144-A CHOLESTEROL OXIDASE AND 3,4-DICHLOROPHENOL BOEHRINGER MANNHEIM GMBH (DE) 1985-03-05 US claimed
JP-57099192-A None JP disclosed
JP-59179075-A None JP disclosed
CN-118270908-A Technology for treating peculiar smell waste gas by cyclic spraying method and cooperatively treating organic wastewater 生态环境部南京环境科学研究所 2024-07-02 CN disclosed
US-20240093211-A1 Modified Bidirectional Catalase Promoter from Bacillus BASF SE (DE) 2024-03-21 US disclosed
CN-113975212-B Processing method for removing harmful substances in bamboo-wood vinegar, wet tissue liquid and mouthwash prepared by processing method 浙江银帆生物科技有限公司 2023-12-12 CN disclosed
US-11788094-B2 Method of increasing catalase expression or activity BASF SE (DE) 2023-10-17 US disclosed
CN-108473994-B Modified bidirectional catalase promoter from Bacillus 巴斯夫欧洲公司 2023-09-01 CN disclosed
CN-113996078-B Simple processing method for concentrated natural organic acid by using biomass dry distillation acid as raw material 浙江农林大学 2023-03-17 CN disclosed
US-20220195069-A1 PCSK9 INHIBITORS FOR NEUROPATHY MANCHESTER UNIV NHS FOUNDATION TRUST (GB) 2022-06-23 US disclosed
EP-0423333-A1 ANTI-ENDOSERINE ANTIBODY Yamasa Shoyu Kabushiki Kaisha (JP) 1991-04-24 EP disclosed
EP-0371712-A2 Bacterial extracellular lignin peroxidase IDAHO RESEARCH FOUNDATION, INC. (US) 1990-06-06 EP disclosed
US-4778753-A IN PRESCENCE OF URICASE, METAL CHELATE AND ANIONIC SURFACTANT; WITHOUT COLORING INTERFERENCE WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 1988-10-18 US disclosed
EP-0243126-A2 Method of measuring hydrogen peroxide or of measuring an enzyme or biochemical substrate liberating the peroxide SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1987-10-28 EP disclosed
US-4610963-A QUANTITATIVE ANALYSIS Takara Suzo Co., Ltd. (JP) 1986-09-09 US disclosed
US-4600689-A Novel bilirubin oxidase, its production and use TAKARA SHUZO CO., LTD. (JP) 1986-07-15 US disclosed
US-4515889-A CENTRIFUGAL FORCE BOEHRINGER MANNHEIM GMBH (DE) 1985-05-07 US disclosed
JP-S59179075-A PREPARATION OF PEROXIDASE OOSAKASHI 1984-10-11 JP disclosed
JP-S5799192-A PREPARATION OF PEROXIDASE UEDA KAGAKU KOGYO KK 1982-06-19 JP disclosed