SCHEMBL128545

SCHEMBL128545

CCC#C[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1680279 0.74
SCHEMBL1894280 0.71
SCHEMBL7109 0.71
SCHEMBL129172 0.69
SCHEMBL31122211 0.67 ALDH1A1 (0.39)
SCHEMBL83896 0.64
Bicarbonate SCHEMBL15967910 0.64 FFAR3 (0.44)
Bicarbonate SCHEMBL167201 0.64 FFAR3 (0.44)
SCHEMBL302044 0.64
Ethyne SCHEMBL5815147 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2197 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402124-A Aryl sulfonamide compound and anti-influenza application thereof 中国医学科学院医药生物技术研究所 2024-01-16 CN claimed
CN-116023322-A N-acetanilide cationic compound, and preparation method and application thereof 天津键凯科技有限公司 2023-04-28 CN claimed
CN-114230457-A 2-benzylidene tetralone derivatives and preparation method and application thereof 中山大学 2022-03-25 CN claimed
EP-3555086-A1 1,4-THIAZINE DIOXIDE AND 1,2,4-THIADIAZINE DIOXIDE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE Amgen Inc. (US) 2019-10-23 EP claimed
US-10112958-B2 N-[2-(2-amino-6,6-disubstituted-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-YL)-1,3-thiazol-4-YL] amides PFIZER INC. (US) 2018-10-30 US claimed
EP-3353183-A1 N-[2-(2-AMINO-6,6-DISUBSTITUTED-4, 4A, 5, 6-TETRAHYDROPYRANO [3,4-D][1,3]THIAZIN-8A (8H)-YL) -1, 3-THIAZOL-4-YL]AMIDES Pfizer Inc (US) 2018-08-01 EP claimed
WO-2018112094-A1 1,4-THIAZINE DIOXIDE AND 1,2,4-THIADIAZINE DIOXIDE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE AMGEN INC. (US) 2018-06-21 WO claimed
US-20170305931-A1 N-[2-(2-AMINO-6,6-DISUBSTITUTED-4,4a,5,6-TETRAHYDROPYRANO[3,4-d][1,3]THIAZIN-8a(8H)-YL)-1,3-THIAZOL-4-YL] AMIDES PFIZER INC. (US) 2017-10-26 US claimed
US-20170088558-A1 N-[2-(2-Amino-6,6-Disubstituted-4,4a,5,6-Tetrahydropyrano[3,4-d][1,3]Thiazin-8a(8H)-YL)-1,3-Thiazol-4-YL]Amides PFIZER INC. (US) 2017-03-30 US claimed
WO-2017051276-A1 N-[2-(2-AMINO-6,6-DISUBSTITUTED-4, 4A, 5, 6-TETRAHYDROPYRANO [3,4-D][1,3] THIAZIN-8A (8H)-YL) -1, 3-THIAZOL-4-YL] AMIDES PFIZER INC. (US) 2017-03-30 WO claimed
EP-0923562-B1 SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS BAYER AG (DE) 2002-10-09 EP claimed
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP claimed
CN-1315952-A Substituted thiazol (in) ylideneamino sulfonylamino (thio) carbonyl-triazolinones BAYER AG (DE) 2001-10-03 CN claimed
EP-0831705-B1 N-ARYL-1,2,4-TRIAZOLIN-5-ONES BAYER AG (DE) 2001-08-29 EP claimed
EP-0906270-B1 PROCESS FOR PRODUCING HYDROXYARENES BAYER AG (DE) 2000-10-25 EP claimed
EP-0784431-B1 SYNERGISTIC ACTIVE SUBSTANCE HERBICIDE COMBINATIONS WITH 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-5-(2-CHLOROPROPIONAMIDO)-4-NITROPYRAZOL BAYER AG (DE) 2000-03-08 EP claimed
US-4988704-A Pyrimidine fungicides for plants KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-01-29 US claimed
EP-0224339-B1 PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING SAME AND AGRICULTURAL OR HORTICULTURAL FUNGICIDAL COMPOSITION CONTAINING SAME KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-01-02 EP claimed
US-4969950-A Triazole compounds and methods for regulating plant growth BASF AKTIENGESELLSCHAFT (DE) 1990-11-13 US claimed
EP-0224339-A2 Pyrimidine derivative, process for preparing same and agricultural or horticultural fungicidal composition containing same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-06-03 EP claimed