Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL15967910 | 1.00 | FFAR3 (0.44) | FFAR3GRIK1GRIK2CA1CA2 | |
| Bicarbonate SCHEMBL16444479 | 0.85 | GRIK1 (0.42) | FFAR3GRIK1GRIK2HDAC1HDAC2 | |
| Bicarbonate SCHEMBL5538707 | 0.83 | — | — | |
| SCHEMBL3110359 | 0.81 | — | — | |
| SCHEMBL3110355 | 0.81 | — | — | |
| Bicarbonate SCHEMBL19260208 | 0.81 | PTPN7 (0.54) | TDP1ALDH1A1KDM4EPTPN7HMGCR | |
| Bicarbonate SCHEMBL872743 | 0.79 | PTPN7 (0.63) | TDP1ALDH1A1KDM4EPTPN7HMGCR | |
| SCHEMBL7109 | 0.78 | — | — | |
| SCHEMBL1894280 | 0.78 | — | — | |
| SCHEMBL10946710 | 0.76 | GRIK1 (0.53) | FFAR3GRIK1GRIK2CA2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250349901-A1 | NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY | LG ENERGY SOLUTION LTD (KR) | 2025-11-13 | — | — | US | claimed |
| EP-3940845-B1 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | NINGDE AMPEREX TECHNOLOGY LTD (CN) | 2025-01-22 | — | — | EP | claimed |
| US-12125983-B2 | Electrolyte and electrochemical device including the same | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2024-10-22 | — | — | US | claimed |
| EP-3940845-A1 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | NingDe Amperex Technology Limited (CN) | 2022-01-19 | — | — | EP | claimed |
| EP-4730479-A2 | FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME | Kyoto University (JP) | 2026-04-22 | — | — | EP | disclosed |
| US-20260031400-A1 | ELECTROLYTE FOR POWER STORAGE DEVICE, REINFORCING AGENT, ELECTROLYTE SOLUTION, AND POWER STORAGE DEVICE USING SAME | TOMIYAMA PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2026-01-29 | — | — | US | disclosed |
| US-20260031394-A1 | ELECTROLYTE FOR POWER STORAGE DEVICE, REINFORCING AGENT, ELECTROLYTE SOLUTION, AND POWER STORAGE DEVICE USING SAME | TOMIYAMA PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2026-01-29 | — | — | US | disclosed |
| EP-4657604-A2 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | Ningde Amperex Technology Limited (CN) | 2025-12-03 | — | — | EP | disclosed |
| EP-4404324-B1 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME | NINGDE AMPEREX TECHNOLOGY LTD (CN) | 2025-11-19 | — | — | EP | disclosed |
| US-20250349901-A1 | NON-AQUEOUS ELECTROLYTE FOR LITHIUM SECONDARY BATTERY | LG ENERGY SOLUTION LTD (KR) | 2025-11-13 | — | — | US | disclosed |
| US-12407022-B2 | Electrolyte and electrochemical device | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2025-09-02 | — | — | US | disclosed |
| US-20250246685-A1 | FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME | KYOTO UNIVERSITY (JP) | 2025-07-31 | — | — | US | disclosed |
| CN-101288199-A | Nonaqueous electrolyte solution and lithium secondary battery using same | MITSUI CHEMICALS INC (JP) | 2008-10-15 | — | — | CN | disclosed |
| CN-101203982-A | Lithium secondary battery | MITSUBISHI CHEM CORP (JP) | 2008-06-18 | — | — | CN | disclosed |
| US-20070178379-A1 | Non-aqueous electrolyte secondary battery and non-aqueous electrolyte | SANYO ELECTRIC CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1806806-A1 | NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY AND NON-AQUEOUS ELECTROLYTE | Sanyo Electric Co., Ltd. (JP) | 2007-07-11 | — | — | EP | disclosed |
| US-20060154149-A1 | Lithium secondary battery | SHIN-KOBE ELECTRIC MACHINERY CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| CN-1249839-C | Additive for electrolytic solution, non-aqueous elecrolytic solution using said additive and secondary cell | MITSUI CHEMICALS INC (JP) | 2006-04-05 | — | — | CN | disclosed |
| CN-1246925-C | Nonaqueous electrolyte secondary battery | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2006-03-22 | — | — | CN | disclosed |
| CN-1369926-A | Nonaqueous electrolyte secondary battery | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2002-09-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260031394-A1 | ELECTROLYTE FOR POWER STORAGE DEVICE, REINFORCING AGENT, ELECTROLYTE SOLUTION, AND POWER STORAGE DEVICE USING SAME | SMC1A, SMC2, SMC4 | FFAR3 4100/4885GRIK1 171/4885GRIK2 276/4885 |
| US-20260031400-A1 | ELECTROLYTE FOR POWER STORAGE DEVICE, REINFORCING AGENT, ELECTROLYTE SOLUTION, AND POWER STORAGE DEVICE USING SAME | KCNN1, KCNN2, ILK | FFAR3 3720/4885GRIK1 133/4885GRIK2 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.