Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.69 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.68 |
| ▸ | SRC | P12931 | 11/20 | 0.68 |
| ▸ | EGFR | P00533 | 9/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.68 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.68 |
| ▸ | STAT5A | P42229 | 1/20 | 0.68 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.68 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.68 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.52 |
| ▸ | KIT | P10721 | 3/20 | 0.52 |
| ▸ | WEE1 | P30291 | 3/20 | 0.48 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL5761899 | 0.84 | FGFR1 (0.62) | ABL1FGFR1SRCEGFRPDGFRB | |
| SCHEMBL16986331 | 0.84 | FGFR1 (0.61) | ABL1FGFR1SRCEGFRPDGFRB | |
| SCHEMBL19662125 | 0.82 | ABL1 (1.00) | ABL1FGFR1SRCEGFRPDGFRB | |
| SCHEMBL29557258 | 0.82 | ABL1 (1.00) | ABL1FGFR1SRCEGFRPDGFRB | |
| SCHEMBL29378902 | 0.81 | SRC (1.00) | ABL1FGFR1SRCEGFRPDGFRB | |
| SCHEMBL29765306 | 0.81 | SRC (1.00) | ABL1FGFR1SRCEGFRPDGFRB | |
| SCHEMBL256711 | 0.81 | SRC (1.00) | ABL1FGFR1SRCEGFRPDGFRB | |
| SCHEMBL30257377 | 0.81 | SRC (1.00) | ABL1FGFR1SRCEGFRPDGFRB | |
| SCHEMBL14161581 | 0.80 | SRC (0.53) | ABL1FGFR1SRCEGFRPDGFRB | |
| Ethane SCHEMBL5793409 | 0.78 | WEE1 (0.54) | ABL1FGFR1SRCEGFRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | disclosed |
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |