Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996622 | 0.77 | GAA (0.31) | IRAK4LMNAPOLBPDE10A | |
| SCHEMBL23367887 | 0.74 | CYP1A2 (0.41) | IRAK4LRRK2CYP1A2LMNAPOLB | |
| SCHEMBL12871753 | 0.74 | GRIA2 (0.35) | LMNAPOLB | |
| SCHEMBL12859196 | 0.74 | — | — | |
| SCHEMBL19987817 | 0.73 | KDM4E (0.39) | IRAK4PDE10A | |
| SCHEMBL18078792 | 0.73 | IRAK4 (0.30) | IRAK4POLB | |
| SCHEMBL26389004 | 0.67 | — | — | |
| SCHEMBL30206254 | 0.66 | ALDH1A1 (0.49) | LRRK2LMNAPOLBPDE10AMYLK2 | |
| SCHEMBL22423423 | 0.66 | DGAT1 (0.31) | — | |
| SCHEMBL14996621 | 0.64 | PDE10A (0.34) | LRRK2PDE10AMYLK2CSF1RMARK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2281810-A1 | AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | Sinochem Corporation (CN) | 2011-02-09 | — | — | EP | disclosed |