Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335470 | 0.97 | KMT2A (0.60) | ALOX5KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL8561986 | 0.93 | KMT2A (0.55) | ALOX5KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL2003642 | 0.90 | KMT2A (0.53) | ALOX5KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL27747363 | 0.90 | KMT2A (0.53) | ALOX5KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL9051523 | 0.90 | NPC1 (0.61) | ALOX5KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL417705 | 0.89 | MAPT (0.60) | ALOX5KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL2825416 | 0.88 | MAPT (0.69) | KMT2ASLC6A2SLC6A3TDP1HTT | |
| SCHEMBL4626752 | 0.88 | KMT2A (0.50) | ALOX5KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL12642453 | 0.88 | KMT2A (0.60) | ALOX5KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL523154 | 0.86 | KMT2A (0.67) | ALOX5KMT2ASLC6A2SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110038805-A1 | COMPOUNDS COMPRISING PARAMAGNETIC CHELATES ARRANGED AROUND A CENTRAL CORE AND THEIR USE IN MAGNETO RESONANCE IMAGING AND SPECTROSCOPY | GE HEALTHCARE AS (NO) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110038805-A1 | COMPOUNDS COMPRISING PARAMAGNETIC CHELATES ARRANGED AROUND A CENTRAL CORE AND THEIR USE IN MAGNETO RESONANCE IMAGING AND SPECTROSCOPY | ABCB7, TSPO, MAG | ALOX5 4409/4885KMT2A 2800/4885SLC6A2 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.