Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335470 | 0.96 | KMT2A (0.60) | KMT2ASLC6A2SLC6A3TDP1ALOX5 | |
| SCHEMBL12856432 | 0.93 | ALOX5 (0.61) | KMT2ASLC6A2SLC6A3TDP1ALOX5 | |
| SCHEMBL9051523 | 0.89 | NPC1 (0.61) | KMT2ASLC6A2SLC6A3TDP1ALOX5 | |
| SCHEMBL27747363 | 0.89 | KMT2A (0.53) | KMT2ASLC6A2SLC6A3TDP1ALOX5 | |
| SCHEMBL312211 | 0.87 | KMT2A (0.72) | KMT2ASLC6A2SLC6A3TDP1RAB9A | |
| SCHEMBL9266925 | 0.87 | KMT2A (0.72) | KMT2ASLC6A2SLC6A3TDP1RAB9A | |
| SCHEMBL2003642 | 0.86 | KMT2A (0.53) | KMT2ASLC6A2SLC6A3TDP1ALOX5 | |
| SCHEMBL417705 | 0.85 | MAPT (0.60) | KMT2ASLC6A2SLC6A3TDP1ALOX5 | |
| SCHEMBL2825416 | 0.84 | MAPT (0.69) | KMT2ASLC6A2SLC6A3TDP1HTT | |
| SCHEMBL4626752 | 0.84 | KMT2A (0.50) | KMT2ASLC6A2SLC6A3TDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719251-B1 | BICYCLO (2.2.2) OCTANE DERIVATIVES CHOLECYSTOKININ AND/OR GASTRIN ANTAGONISTS | BLACK JAMES FOUNDATION (GB) | 1998-12-09 | — | — | EP | disclosed |
| US-5795907-A | Gastin and CCK receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1998-08-18 | — | — | US | disclosed |
| EP-0720601-A1 | GASTRIN AND CCK RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995004720-A2 | GASTRIN AND CCK RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 1995-02-16 | — | — | WO | disclosed |