Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CCR6 | P51684 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29007688 | 0.79 | TDP1 (0.49) | TSHRTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4632603 | 0.79 | ALDH1A1 (0.38) | TSHRTDP1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL11320325 | 0.78 | GPR35 (0.42) | CYP1A2TSHRTDP1L3MBTL1GPR35 | |
| SCHEMBL28819215 | 0.77 | ALDH1A1 (0.59) | CYP1A2TSHRTDP1L3MBTL1GPR35 | |
| SCHEMBL18744865 | 0.76 | TSHR (0.39) | CYP1A2TSHRTDP1L3MBTL1GPR35 | |
| SCHEMBL8099774 | 0.76 | ALDH1A1 (0.52) | TSHRTDP1L3MBTL1GPR35ALDH1A1 | |
| SCHEMBL31124783 | 0.76 | TSHR (0.49) | CYP1A2TSHRTDP1L3MBTL1GPR35 | |
| SCHEMBL1311698 | 0.74 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL11133854 | 0.74 | CYP1A2 (0.67) | CYP1A2TSHRTDP1GPR35ALDH1A1 | |
| SCHEMBL30054130 | 0.74 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7880006-B2 | 4-Acetoxy-5-chloro-6-(4-chlorophenoxy)-2,3-dimethyl-quinoline, used as agricultural and horticultural insecticides | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-02-01 | — | — | US | disclosed |