Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.46 |
| ▸ | PER2 | O15055 | 1/20 | 0.46 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.46 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093003 | 0.86 | BACE1 (0.62) | KDM4EALDH1A1SMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL10257256 | 0.79 | ALDH1A1 (0.90) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL410782 | 0.77 | ALDH1A1 (0.78) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL411198 | 0.75 | ALDH1A1 (1.00) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL411197 | 0.75 | ALDH1A1 (0.75) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15570508 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL411693 | 0.73 | ALDH1A1 (1.00) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18862339 | 0.73 | KDM4E (0.97) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL409536 | 0.72 | MAPT (0.80) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21093337 | 0.71 | RAD52 (0.53) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028719-A1 | SCREENING METHODS FOR AMYLOID BETA MODULATORS | WARATAH PHARMACEUTICALS INC. (CA) | 2011-02-03 | — | — | US | disclosed |
| US-20110028719-A1 | SCREENING METHODS FOR AMYLOID BETA MODULATORS | WARATAH PHARMACEUTICALS INC. (CA) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028719-A1 | SCREENING METHODS FOR AMYLOID BETA MODULATORS | APP, BACE1, IAPP | KDM4E 4738/4885ALDH1A1 4135/4885MEN1 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.